环香豆素结构式
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常用名 | 环香豆素 | 英文名 | pyranocoumarin |
|---|---|---|---|---|
| CAS号 | 518-20-7 | 分子量 | 322.35500 | |
| 密度 | 1.27g/cm3 | 沸点 | 488.6ºC at 760 mmHg | |
| 分子式 | C20H18O4 | 熔点 | 166° | |
| MSDS | 中文版 美版 | 闪点 | 216.2ºC | |
| 符号 |
GHS06 |
信号词 | Danger |
环香豆素用途Cyclocumarol is an anticoagulant similar to but less potent than warfarin. This product may cause hemorrhaging if used indiscriminately. |
| 中文名 | 环香豆素 |
|---|---|
| 英文名 | 2-methoxy-2-methyl-4-phenyl-3,4-dihydropyrano[3,2-c]chromen-5-one |
| 中文别名 | 吡喃香豆素 |
| 英文别名 | 更多 |
| 密度 | 1.27g/cm3 |
|---|---|
| 沸点 | 488.6ºC at 760 mmHg |
| 熔点 | 166° |
| 分子式 | C20H18O4 |
| 分子量 | 322.35500 |
| 闪点 | 216.2ºC |
| 精确质量 | 322.12100 |
| PSA | 48.67000 |
| LogP | 4.07000 |
| InChIKey | ZGFASEKBKWVCGP-UHFFFAOYSA-N |
| SMILES | COC1(C)CC(c2ccccc2)c2c(c3ccccc3oc2=O)O1 |
| 折射率 | 1.624 |
| 符号 |
GHS06 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H310 |
| 警示性声明 | P262-P280-P302 + P352 + P310-P361 + P364 |
| 个人防护装备 | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| 危害码 (欧洲) | T+ |
| 风险声明 (欧洲) | 27 |
| 安全声明 (欧洲) | 28-36/37-45 |
| 危险品运输编码 | UN 2811 |
| RTECS号 | UQ0335200 |
| 包装等级 | III |
| 危险类别 | 6.1(b) |
| 海关编码 | 2932999099 |
| 海关编码 | 2932999099 |
|---|---|
| 中文概述 | 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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The preferred solution conformation of warfarin at the active site of cytochrome P-450 based on the CD spectra in octanol/water model system.
J. Med. Chem. 27(8) , 1092-5, (1984) An octanol/water model system and circular dichroism (CD) spectroscopy have been used to study the solution conformation of warfarin in aqueous and lipid environments. Upon partitioning of (S)-warfari... |
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Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9.
Arch. Biochem. Biophys. 372(1) , 16-28, (1999) Possible reasons for the observed differences in metabolic behavior and drug interaction liability between the structurally similar oral anticoagulants warfarin and phenprocoumon were explored. Incuba... |
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Inhibitory effect of coumarins on HIV-1 replication and cell-mediated or cell-free viral transmission.
Acta Virol. 37(4) , 241-50, (1993) A single dose of coumarin derivatives, warfarin, 4-hydroxycoumarin and umbelliferone, added at the time of inoculation either by free virus or by contact with U1 monocytes exhibited a dose-dependent i... |
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实验名称:Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production ...
来源:ChEMBL
靶标:Prostaglandin G/H synthase 2
External Id:CHEMBL4148151
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实验名称:qHTS for Inhibitors of Polymerase Kappa
来源:NCGC
靶标:DNA polymerase kappa [Homo sapiens]
External Id:PolK100
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实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
来源:The Scripps Research Institute Molecular Screening Center
External Id:MITF_INH_Alpha_1536_1X%INH PRUN
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实验名称:qHTS for Inhibitors of binding or entry into cells for Marburg Virus
来源:NCGC
靶标:gene 4 small orf - Marburg virus
External Id:VSVM-OFFLINE
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实验名称:qHTS for Inhibitors of binding or entry into cells for Lassa Virus
来源:NCGC
靶标:N/A
External Id:VSVL-OFFLINE
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| Pyranocumarin [German] |
| Cumopyran |
| Compound 63 link |
| CYCLOCUMAROL |
| Methanopyranorin |
| Cyclocoumarol |
| Anticoagulans 63 |
| BL 5 |
| Cumopyrin |
| Pyranocoumarin |