扁枝衣二酸

• 常用名: 扁枝衣二酸
• 英文名: Evernic Acid
• CAS号: 537-09-7
• 分子量: 332.30500
• 密度: 1.391g/cm3
• 沸点: 531.8ºC at 760mmHg
• 分子式: C₁₇H₁₆O₇
• 熔点: 166-167ºC
• 闪点: 194.6ºC

扁枝衣二酸用途

Evernic Acid是地衣产生的次生代谢产物,包括Ramalina、Evernia和Hypogymnia,一些研究已经描述了其抗癌、抗真菌和抗菌作用。神经保护和抗炎作用[1]。

扁枝衣二酸名称

• 中文名: 扁枝衣二酸
• 英文名: 2-hydroxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoic acid
• 中文别名: 煤地衣酸

扁枝衣二酸生物活性

• 描述: Evernic Acid是地衣产生的次生代谢产物,包括Ramalina、Evernia和Hypogymnia,一些研究已经描述了其抗癌、抗真菌和抗菌作用。神经保护和抗炎作用[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Fungal Metabolite

• 参考文献:

  [1]. Lee S, et al. Neuroprotective and Anti-Inflammatory Effects of Evernic Acid in an MPTP-Induced Parkinson's Disease Model. Int J Mol Sci. 2021;22(4):2098. Published 2021 Feb 20.

扁枝衣二酸物理化学性质

• 密度: 1.391g/cm3
• 沸点: 531.8ºC at 760mmHg
• 熔点: 166-167ºC
• 分子式: C₁₇H₁₆O₇
• 分子量: 332.30500
• 闪点: 194.6ºC
• 精确质量: 332.09000
• PSA: 113.29000
• LogP: 2.64060
• InChIKey: GODLCSLPZIBRMG-UHFFFAOYSA-N
• SMILES: COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2)c(O)c1
• 折射率: 1.576
• 储存条件: -20°C，密闭，干燥
• 计算化学:

  1.疏水参数计算参考值（XlogP）:4

  2.氢键供体数量:3

  3.氢键受体数量:7

  4.可旋转化学键数量:5

  5.互变异构体数量:169

  6.拓扑分子极性表面积:113

  7.重原子数量:24

  8.表面电荷:0

  9.复杂度:466

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

扁枝衣二酸毒性和生态

扁枝衣二酸安全信息

• 海关编码: 2918990090

扁枝衣二酸海关

• 海关编码: 2918990090
• 中文概述: 2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

扁枝衣二酸靶点实验

查看更多实验

实验名称：Toxicity against neonate larval stage of Spodoptera littoralis fed with diet containi... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3057995

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Growth retarding activity against neonate larval stage of Spodoptera littoralis fed w... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3058022

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

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扁枝衣二酸英文别名

• EINECS 208-658-2
• Lecanoric acid methyl ether
• Evernic acid,pruiss
• Monomethylaether-p-diorsellinsaeure
• 2-hydroxy-4-methoxy-6-methylbenzoic acid 4'-carboxy-3'-hydroxy-5'-methylphenyl ester
• Evernic acid
• Monomethylaether-lecanorsaeure