CGP 13501

• 常用名: CGP 13501
• 英文名: CGP 13501
• CAS号: 56189-68-5
• 分子量: 290.44
• 密度: 0.965g/cm3
• 沸点: 344.8ºC at 760 mmHg
• 分子式: C₁₉H₃₀O₂
• 熔点: N/A
• 闪点: 146.8ºC

CGP 13501用途

CGP13501 是 GABAB 受体 的正变构调节剂。CGP13501 是异丙酚的结构类似物。

CGP 13501名称

• 英文名: 3-(3,5-di-tert-butyl-4-hydroxyphenyl)-2,2-dimethyl-propionaldehyde

CGP 13501生物活性

• 描述: CGP13501 是 GABAB 受体 的正变构调节剂。CGP13501 是异丙酚的结构类似物。
• 相关类别:
  信号通路 >> 跨膜转运 >> GABA受体
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> GABA受体
• 靶点实验:

  GABAB receptor[1]

• 参考文献:

  [1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001 Nov;60(5):963-71.

CGP 13501物理化学性质

• 密度: 0.965g/cm3
• 沸点: 344.8ºC at 760 mmHg
• 分子式: C₁₉H₃₀O₂
• 分子量: 290.44
• 闪点: 146.8ºC
• 精确质量: 290.22500
• PSA: 37.30000
• LogP: 4.75480
• InChIKey: XGWATTXMMMANFJ-UHFFFAOYSA-N
• SMILES: CC(C)(C=O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1
• 折射率: 1.499

CGP 13501安全信息

• WGK德国: 3

CGP 13501靶点实验

查看更多实验

实验名称：qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali... 来源：NCGC External Id：adst_MBL_Abs_LOPAC_o1

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1266185

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2... 来源：NCGC 靶标：ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] External Id：UBCH001

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

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