(2R,3S,3AS)-2-(1,3-苯并二氧戊环-5-基)-3,3A-二氢-5-甲氧基-3-甲基-3A-(2-丙烯-1-基)-6(2H)-苯并呋喃酮

• 常用名: (2R,3S,3AS)-2-(1,3-苯并二氧戊环-5-基)-3,3A-二氢-5-甲氧基-3-甲基-3A-(2-丙烯-1-基)-6(2H)-苯并呋喃酮
• 英文名: Burchellin
• CAS号: 57457-99-5
• 分子量: 340.37
• 密度: 1.3±0.1 g/cm3
• 沸点: 491.0±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₀O₅
• 熔点: N/A
• 闪点: 216.4±28.8 °C

用途

cis-Burchellin 是一种具有抗过敏活性的生物活性新木质素。cis-Burchellin 抑制 Jurkat t 细胞 IL-2 生成。

名称

• 中文名: (2R,3S,3AS)-2-(1,3-苯并二氧戊环-5-基)-3,3A-二氢-5-甲氧基-3-甲基-3A-(2-丙烯-1-基)-6(2H)-苯并呋喃酮
• 英文名: (2R,3S,3aS)-3a-allyl-2-(benzo[d][1,3]dioxol-5-yl)-5-methoxy-3-methyl-3,3a-dihydrobenzofuran-6(2H)-one

生物活性

• 描述: cis-Burchellin 是一种具有抗过敏活性的生物活性新木质素。cis-Burchellin 抑制 Jurkat t 细胞 IL-2 生成。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Thi Tuyet Mai Nguyen, et al. Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells. Natural Product Sciences

物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 491.0±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₀O₅
• 分子量: 340.37
• 闪点: 216.4±28.8 °C
• 精确质量: 340.131073
• PSA: 53.99000
• LogP: 3.05
• InChIKey: SOLJFAQVSWXZEQ-TVNIXMEMSA-N
• SMILES: C=CCC12C=C(OC)C(=O)C=C1OC(c1ccc3c(c1)OCO3)C2C
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.603
• 储存条件: 2-8℃，干燥，密闭

安全信息

• 危害码 (欧洲): Xi

靶点实验

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英文别名

• (2R,3S,3aS)-3a-Allyl-2-(1,3-benzodioxol-5-yl)-5-methoxy-3-methyl-3,3a-dihydro-1-benzofuran-6(2H)-one
• Burchellin