昆明鸡血藤素

• 常用名: 昆明鸡血藤素
• 英文名: auriculasin
• CAS号: 60297-37-2
• 分子量: 420.45
• 密度: 1.314g/cm3
• 沸点: 668ºC at 760 mmHg
• 分子式: C₂₅H₂₄O₆
• 熔点: N/A
• 闪点: 231.2ºC

昆明鸡血藤素用途

木耳蛋白酶是从细叶补血草中分离得到的天然产物。耳廓蛋白酶对大麻素受体1型(CB1)具有活性,IC50值为8.92µM【1】。

昆明鸡血藤素名称

• 中文名: 昆明鸡血藤素
• 英文名: 7-(3,4-dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-10-(3-methylbut-2-enyl)pyrano[3,2-g]chromen-6-one

昆明鸡血藤素生物活性

• 描述: 木耳蛋白酶是从细叶补血草中分离得到的天然产物。耳廓蛋白酶对大麻素受体1型(CB1)具有活性,IC50值为8.92µM【1】。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 大麻素受体
• 靶点实验:

  CB1:8.92 μM (IC50)

• 参考文献:

  [1]. Dizamatova A, et al. A New Prenylated Isoflavonoid From Limonium leptophyllum. Natural Product Communications. May 2019.

昆明鸡血藤素物理化学性质

• 密度: 1.314g/cm3
• 沸点: 668ºC at 760 mmHg
• 分子式: C₂₅H₂₄O₆
• 分子量: 420.45
• 闪点: 231.2ºC
• 精确质量: 420.15700
• PSA: 100.13000
• LogP: 5.26970
• InChIKey: PSEBCAMYGWGJMH-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1c2c(c(O)c3c(=O)c(-c4ccc(O)c(O)c4)coc13)C=CC(C)(C)O2
• 外观性状: 粉末
• 折射率: 1.644
• 储存条件: 室温

昆明鸡血藤素安全信息

• 危害码 (欧洲): Xi

昆明鸡血藤素靶点实验

查看更多实验

实验名称：Antibacterial activity against Pseudomonas aeruginosa TISTR 292 by 2-fold serial dilu... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4200351

实验名称：Antibacterial activity against Salmonella typhimurium TISTR 781 by 2-fold serial dilu... 来源：ChEMBL 靶标：Salmonella enterica subsp. enterica serovar Typhimurium External Id：CHEMBL4200350

实验名称：Antibacterial activity against Bacillus subtilis TISTR 008 by 2-fold serial dilution ... 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL4200347

实验名称：Antibacterial activity against Staphylococcus epidermidis ATCC 12228 by 2-fold serial... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL4200349

实验名称：Antibacterial activity against Staphylococcus aureus TISTR 1466 by 2-fold serial dilu... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4200348

实验名称：Inhibition of DMBA-induced/TPA-promoted carcinogenesis in ICR mouse assessed as mouse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL987508

实验名称：Inhibition of DMBA-induced/TPA-promoted carcinogenesis in ICR mouse assessed as mouse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL987507

实验名称：Inhibition of DMBA-induced/TPA-promoted carcinogenesis in ICR mouse assessed as numbe... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL987510

实验名称：Inhibition of DMBA-induced/TPA-promoted carcinogenesis in ICR mouse assessed as numbe... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL987509

实验名称：Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by s... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL3755949

共14条，当前第1页，共2页

1

2

昆明鸡血藤素英文别名

• 7-(3,4-Dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-10-(3-methyl-2-buten-1-yl)-2H,6H-pyrano[3,2-g]chromen-6-one
• AURICULASIN
• auriculatin