氟甲氮平

• 常用名: 氟甲氮平
• 英文名: Flumezapine
• CAS号: 61325-80-2
• 分子量: 330.42300
• 密度: 1.383g/cm3
• 沸点: 479.498ºC at 760 mmHg
• 分子式: C₁₇H₁₉FN₄S
• 熔点: N/A
• 闪点: 243.792ºC

氟甲氮平名称

• 中文名: 氟甲氮平
• 英文名: 7-fluoro-2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine

氟甲氮平物理化学性质

• 密度: 1.383g/cm3
• 沸点: 479.498ºC at 760 mmHg
• 分子式: C₁₇H₁₉FN₄S
• 分子量: 330.42300
• 闪点: 243.792ºC
• 精确质量: 330.13100
• PSA: 59.11000
• LogP: 3.02770
• 折射率: 1.697

氟甲氮平毒性和生态

氟甲氮平靶点实验

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实验名称：Tested for physostigmine lethality at a dose of 2.5 mg/kg after oral administration i... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL743061

实验名称：Compound was assessed for its ability to block a conditioned avoidance response; Dose... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL775310

实验名称：Displacement of [3H]spiroperidol from Dopamine receptor of rat striatum membrane 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL672127

实验名称：Tested for physostigmine lethality at a dose of 5 mg/kg after oral administration in ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL738708

实验名称：Rotarod response in rat to assess muscular incoordination (following p.o. dosing) 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL775217

实验名称：Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, ... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M2 External Id：CHEMBL744142

实验名称：Compound administered perorally was evaluated for the conditioned avoidance response ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL775219

实验名称：Inhibition of [3H]QNB binding to muscarinic cholinergic receptor from male Olac rat b... 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M2 External Id：CHEMBL744002

实验名称：compound behavior in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL779450

实验名称：Displacement of [3H]QNB from Muscarinic acetylcholine receptor of rat brain membrane 来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M2 External Id：CHEMBL746568

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氟甲氮平英文别名

• Flumezapinum [INN-Latin]
• Flumezapine (USAN)
• Flumezapinum
• 10H-Thieno(2,3-b)(1,5)benzodiazepine,7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)
• Flumezapina [INN-Spanish]
• 7-fluoro-2-methyl-4-(4-methyl-piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine
• Flumezapina
• FLUMEZAPINE
• 7-Fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine