Flumezapine

Modify Date: 2025-09-18 23:52:53

Flumezapine structure	Common Name	Flumezapine
	CAS Number	61325-80-2	Molecular Weight	330.42300
	Density	1.383g/cm3	Boiling Point	479.498ºC at 760 mmHg
	Molecular Formula	C₁₇H₁₉FN₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	243.792ºC

Name	7-fluoro-2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
Synonym	More Synonyms

Density	1.383g/cm3
Boiling Point	479.498ºC at 760 mmHg
Molecular Formula	C₁₇H₁₉FN₄S
Molecular Weight	330.42300
Flash Point	243.792ºC
Exact Mass	330.13100
PSA	59.11000
LogP	3.02770
Index of Refraction	1.697

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ9007100

CHEMICAL NAME :: 10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-

CAS REGISTRY NUMBER :: 61325-80-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H19-F-N4-S

MOLECULAR WEIGHT :: 330.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,878,1980

methylpiperazine

CAS#:109-01-3

7-fluoro-2-meth...

CAS#:61325-55-1

~35%

Flumezapine

CAS#:61325-80-2

Literature: Chakrabarti, Jiban K.; Horsman, Linda; Hotten, Terrence M.; Pullar, Ian A.; Tupper, David E. Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 878 - 884

Precursor 2
CAS#:109-01-3 methylpiperazine CAS#:61325-55-1 7-fluoro-2-meth...
DownStream 0

Name: Tested for physostigmine lethality at a dose of 2.5 mg/kg after oral administration i...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL743061

Name: Compound was assessed for its ability to block a conditioned avoidance response; Dose...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL775310

Name: Displacement of [3H]spiroperidol from Dopamine receptor of rat striatum membrane
Source: ChEMBL
Target: D(2) dopamine receptor
External Id: CHEMBL672127

Name: Tested for physostigmine lethality at a dose of 5 mg/kg after oral administration in ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL738708

Name: Rotarod response in rat to assess muscular incoordination (following p.o. dosing)
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL775217

Name: Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, ...
Source: ChEMBL
Target: Muscarinic acetylcholine receptor M2
External Id: CHEMBL744142

Name: Compound administered perorally was evaluated for the conditioned avoidance response ...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL775219

Name: Inhibition of [3H]QNB binding to muscarinic cholinergic receptor from male Olac rat b...
Source: ChEMBL
Target: Muscarinic acetylcholine receptor M2
External Id: CHEMBL744002

Name: compound behavior in rat
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL779450

Name: Displacement of [3H]QNB from Muscarinic acetylcholine receptor of rat brain membrane
Source: ChEMBL
Target: Muscarinic acetylcholine receptor M2
External Id: CHEMBL746568

Total 22, Current Page 1 of 3

Flumezapinum [INN-Latin]

Flumezapine (USAN)

Flumezapinum

10H-Thieno(2,3-b)(1,5)benzodiazepine,7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)

Flumezapina [INN-Spanish]

7-fluoro-2-methyl-4-(4-methyl-piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine

Flumezapina

FLUMEZAPINE

7-Fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Flumezapine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

Flumezapine suppliers

Flumezapine price

Flumezapine

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

FlumezapineBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.