顺式白藜芦醇

• 常用名: 顺式白藜芦醇
• 英文名: trans-resveratrol
• CAS号: 61434-67-1
• 分子量: 228.243
• 密度: 1.4±0.1 g/cm3
• 沸点: 449.1±14.0 °C at 760 mmHg
• 分子式: C₁₄H₁₂O₃
• 熔点: 167-170ºC (dec)
• 闪点: 222.3±14.7 °C

顺式白藜芦醇用途

顺式白藜芦醇具有显著的抗病毒活性。顺式白藜芦醇对柯萨奇病毒B3(CVB3)和肠道病毒71(EV71)的IC50分别为12.2µM和37.6µM,可抑制肠道病毒[1]。

顺式白藜芦醇名称

• 中文名: 顺式白藜芦醇
• 英文名: 5-[(Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

顺式白藜芦醇生物活性

• 描述: 顺式白藜芦醇具有显著的抗病毒活性。顺式白藜芦醇对柯萨奇病毒B3(CVB3)和肠道病毒71(EV71)的IC50分别为12.2µM和37.6µM,可抑制肠道病毒[1]。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. Mira Oh, et al. Chemical components from the twigs of Caesalpinia latisiliqua and their antiviral activity. J Nat Med. 2020 Jan;74(1):26-33.

顺式白藜芦醇物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 449.1±14.0 °C at 760 mmHg
• 熔点: 167-170ºC (dec)
• 分子式: C₁₄H₁₂O₃
• 分子量: 228.243
• 闪点: 222.3±14.7 °C
• 精确质量: 228.078644
• PSA: 60.69000
• LogP: 3.14
• InChIKey: LUKBXSAWLPMMSZ-UPHRSURJSA-N
• SMILES: Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1
• 外观性状: 灰白色固体
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.763
• 储存条件: 2-8°C，惰性气体

顺式白藜芦醇安全信息

• 危害码 (欧洲): Xi

顺式白藜芦醇靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Cytotoxicity against human A498 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：A498 External Id：CHEMBL1072626

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity 来源：ChEMBL 靶标：N/A External Id：CHEMBL996580

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL1105822

实验名称：Growth inhibition of human KM20L2 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：KM-20L2 External Id：CHEMBL1105821

实验名称：Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：NCI-H460 External Id：CHEMBL1105820

实验名称：Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：SF-268 External Id：CHEMBL1105819

实验名称：Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1105818

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顺式白藜芦醇英文别名

• 5-[(E)-2-(4-Hydroxyphenyl)ethenyl]benzol-1,3-diol
• cis-3,4',5-trihydroxystilbene
• 5-[(Z)-2-(4-Hydroxyphenyl)vinyl]benzene-1,3-diol
• (E)-5-(p-Hydroxystyryl)resorcinol
• 5-[(Z)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol
• 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
• (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol
• 3,5,4'-Trihydroxy-trans-stilbene
• Resveratrol,Z
• 5-[(E)-2-(4-Hydroxyphenyl)vinyl]benzene-1,3-diol
• cis-resveratrol
• 3,4',5-trihydroxy-stilbene
• Resveratrol
• 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
• 5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol
• 3,4',5-trihydroxystilbene
• (E)-5-(4-hydroxystyryl)benzene-1,3-diol
• 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
• 3,5,4'-trihydroxy-stilbene
• Tocris-1418