WEE1-IN-4

• 常用名: WEE1-IN-4
• 英文名: Wee1 Inhibitor I
• CAS号: 622855-37-2
• 分子量: 362.76600
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₁ClN₂O₃
• 熔点: N/A
• 闪点: N/A

WEE1-IN-4用途

WEE1-IN-4是一种有效的检查点WEE1激酶抑制剂,IC50为0.011μM[1]。

WEE1-IN-4名称

• 中文名: Wee1抑制剂
• 英文名: 4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione

WEE1-IN-4生物活性

• 描述: WEE1-IN-4是一种有效的检查点WEE1激酶抑制剂,IC50为0.011μM[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> WEE1
• 靶点实验:

  IC50: 0.011 μM (Wee1 kinase) pIC50: 7.96[1]

• 参考文献:

  [1]. Kanin Wichapong, et al. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.

WEE1-IN-4物理化学性质

• 分子式: C₂₀H₁₁ClN₂O₃
• 分子量: 362.76600
• 精确质量: 362.04600
• PSA: 85.68000
• LogP: 4.24110
• InChIKey: DPEXRCOBPACFOO-UHFFFAOYSA-N
• SMILES: O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1[nH]c3ccc(O)cc3c21
• 储存条件: 2-8°C，密封，干燥

WEE1-IN-4靶点实验

查看更多实验

实验名称：SANGER: Inhibition of human NCI-H1437 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1437 External Id：CHEMBL2363473

实验名称：SANGER: Inhibition of human NCI-H1299 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1299 External Id：CHEMBL2363467

实验名称：SANGER: Inhibition of human NCI-H1155 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1155 External Id：CHEMBL2363465

实验名称：SANGER: Inhibition of human NCI-H1092 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1092 External Id：CHEMBL2363464

实验名称：SANGER: Inhibition of human NCI-H1395 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1395 External Id：CHEMBL2363470

实验名称：SANGER: Inhibition of human NCI-H1355 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1355 External Id：CHEMBL2363469

实验名称：SANGER: Inhibition of human NCI-H1304 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1304 External Id：CHEMBL2363468

实验名称：SANGER: Inhibition of human NCI-H1693 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1693 External Id：CHEMBL2363484

实验名称：SANGER: Inhibition of human NCI-H1666 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1666 External Id：CHEMBL2363483

实验名称：SANGER: Inhibition of human NCI-H1651 cell growth in a cell viability assay. 来源：ChEMBL 靶标：NCI-H1651 External Id：CHEMBL2363482

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WEE1-IN-4英文别名

• Wee1 Inhibitor
• Kinome_3672
• HMS3229P19