PEO-IAA

• 常用名: PEO-IAA
• 英文名: 2-indol-3-yl-4-oxo-4-phenylbutanoic acid
• CAS号: 6266-66-6
• 分子量: 293.31700
• 密度: 1.318 g/cm3
• 沸点: 569ºC at 760 mmHg
• 分子式: C₁₈H₁₅NO₃
• 熔点: N/A
• 闪点: 297.9ºC

PEO-IAA用途

PEO-IAA 是一种吲哚-3-乙酸 (IAA) 拮抗剂,是一种生长素拮抗剂,可与转运抑制剂响应蛋白 1/生长素信号 F-box 蛋白 (TIR1/AFBs) 结合。

PEO-IAA名称

• 中文名: 2-(1H-吲哚-3-基)-4-氧基-4-苯基亮氨酸
• 英文名: 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid

PEO-IAA生物活性

• 描述: PEO-IAA 是一种吲哚-3-乙酸 (IAA) 拮抗剂,是一种生长素拮抗剂,可与转运抑制剂响应蛋白 1/生长素信号 F-box 蛋白 (TIR1/AFBs) 结合。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
• 体外研究: PEO-IAA也是α-烷基-IAA,并且在生长素响应基因表达以及通过SCFTIR1/AFB介导的细胞分裂和延伸途径中显示出更有效的抗生长素活性。 PEO-IAA不仅抑制生长素响应性ZmSAUR2基因的表达,还抑制重力曲率。 PEO-IAA阻断拟南芥,水稻,苔藓和玉米中的生长素反应[1]。
• 参考文献:

  [1]. Nishimura T, et al. Differential downward stream of auxin synthesized at the tip has a key role in gravitropic curvature via TIR1/AFBs-mediated auxin signaling pathways. Plant Cell Physiol. 2009 Nov;50(11):1874-85.

PEO-IAA物理化学性质

• 密度: 1.318 g/cm3
• 沸点: 569ºC at 760 mmHg
• 分子式: C₁₈H₁₅NO₃
• 分子量: 293.31700
• 闪点: 297.9ºC
• 精确质量: 293.10500
• PSA: 70.16000
• LogP: 3.60910
• InChIKey: SJVMWLJNHPHNPT-UHFFFAOYSA-N
• SMILES: O=C(CC(C(=O)O)c1c[nH]c2ccccc12)c1ccccc1
• 储存条件: 2-8℃

PEO-IAA安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 25
• 安全声明 (欧洲): 45
• 海关编码: 2933990090

PEO-IAA海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

PEO-IAA靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Validation... 来源：NMMLSC 靶标：ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens] External Id：UNMCMD_ABCB6_1o_ValidationSet

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PEO-IAA英文别名

• 2-(1H-indol-3-yl)-4-oxo-4-phenylbutanoic acid