2-indol-3-yl-4-oxo-4-phenylbutanoic acid

Modify Date: 2025-08-26 18:14:00

2-indol-3-yl-4-oxo-4-phenylbutanoic acid Structure
2-indol-3-yl-4-oxo-4-phenylbutanoic acid structure
Common Name 2-indol-3-yl-4-oxo-4-phenylbutanoic acid
CAS Number 6266-66-6 Molecular Weight 293.31700
Density 1.318 g/cm3 Boiling Point 569ºC at 760 mmHg
Molecular Formula C18H15NO3 Melting Point N/A
MSDS N/A Flash Point 297.9ºC

 Use of 2-indol-3-yl-4-oxo-4-phenylbutanoic acid


PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).

 Names

Name 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid
Synonym More Synonyms

 2-indol-3-yl-4-oxo-4-phenylbutanoic acid Biological Activity

Description PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
Related Catalog
In Vitro PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCFTIR1/AFBs. PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize[1].
References

[1]. Nishimura T, et al. Differential downward stream of auxin synthesized at the tip has a key role in gravitropic curvature via TIR1/AFBs-mediated auxin signaling pathways. Plant Cell Physiol. 2009 Nov;50(11):1874-85.

 Chemical & Physical Properties

Density 1.318 g/cm3
Boiling Point 569ºC at 760 mmHg
Molecular Formula C18H15NO3
Molecular Weight 293.31700
Flash Point 297.9ºC
Exact Mass 293.10500
PSA 70.16000
LogP 3.60910
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi
Risk Phrases 25
Safety Phrases 45
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(1H-indol-3-yl)-4-oxo-4-phenylbutanoic acid
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Price: ¥770/10 mM * 1 mL in DMSO

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