戈米辛G

• 常用名: 戈米辛G
• 英文名: gomisin G
• CAS号: 62956-48-3
• 分子量: 536.570
• 密度: 1.3±0.1 g/cm3
• 沸点: 670.9±55.0 °C at 760 mmHg
• 分子式: C₃₀H₃₂O₉
• 熔点: N/A
• 闪点: 217.2±25.0 °C

戈米辛G用途

戈米辛G(Gomisin G)是一抗HIV活性的天然化合物。

戈米辛G名称

• 中文名: 戈米辛G
• 英文名: gomisin G
• 中文别名: 木兰科植物五味子的干燥成熟果实

戈米辛G生物活性

• 描述: 戈米辛G(Gomisin G)是一抗HIV活性的天然化合物。
• 相关类别:
  信号通路 >> 抗感染 >> HIV
  天然产物 >> 苯丙酸类
  研究领域 >> 感染
• 参考文献:

  [1]. Chen DF, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23.

  [2]. Ikeya Y, et al. The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem Pharm Bull (Tokyo). 1979 Jun;27(6):1383-94.

戈米辛G物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 670.9±55.0 °C at 760 mmHg
• 分子式: C₃₀H₃₂O₉
• 分子量: 536.570
• 闪点: 217.2±25.0 °C
• 精确质量: 536.204651
• PSA: 101.91000
• LogP: 6.38
• InChIKey: OFDWKHIQKPKRKY-DSASHONVSA-N
• SMILES: COc1cc2c(c(OC)c1OC)-c1c(cc3c(c1OC)OCO3)C(OC(=O)c1ccccc1)C(C)(O)C(C)C2
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.623
• 储存条件: 2-8℃

戈米辛G靶点实验

查看更多实验

实验名称：Inhibition of 0.2 ug/ml PHA-stimulated human PBMC proliferation assessed as [3H]thymi... 来源：ChEMBL 靶标：PBMC External Id：CHEMBL1113194

实验名称：Inhibition of human PBMC proliferation assessed as [3H]thymidine uptake at 100 uM aft... 来源：ChEMBL 靶标：PBMC External Id：CHEMBL1113193

实验名称：Cytotoxicity against human BT549 cells upto 48 uM 来源：ChEMBL 靶标：BT-549 External Id：CHEMBL977843

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1005254

实验名称：Cytotoxicity against human KB cells upto 48 uM 来源：ChEMBL 靶标：KB External Id：CHEMBL977842

实验名称：Antiinflammatory activity against LPS-induced prostaglandin E2 production in mouse ma... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL977845

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1005256

实验名称：Cytotoxicity against human SKOV3 cells upto 48 uM 来源：ChEMBL 靶标：SK-OV-3 External Id：CHEMBL977844

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1005255

实验名称：Therapeutic index, ratio of IC50 for human H9 cells to EC50 for HIV 3B 来源：ChEMBL 靶标：N/A External Id：CHEMBL1176168

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戈米辛G英文别名

• (6S,7S,8S)-7-Hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-8-yl benzoate
• UNII:6B4CV8T31X
• The dried fruit of Schisandra chinensis