血栓素B1

• 常用名: 血栓素B1
• 英文名: Thromboxane B1
• CAS号: 64626-32-0
• 分子量: 372.496
• 密度: 1.2±0.1 g/cm3
• 沸点: 577.1±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₆O₆
• 熔点: N/A
• 闪点: 196.6±23.6 °C

血栓素B1用途

血栓素B1(TXB1)是血栓素B(TXB)家族成员之一。血栓素是脂质家族的一员,被称为花生四烯酸。血栓素因其在血凝块形成(血栓形成)中的作用而得名。

血栓素B1名称

• 中文名: 血栓素B1
• 英文名: 7-[(2R,3S,4S)-4,6-dihydroxy-2-[(3S)-3-hydroxyoct-1-enyl]oxan-3-yl]heptanoic acid

血栓素B1生物活性

• 描述: 血栓素B1(TXB1)是血栓素B(TXB)家族成员之一。血栓素是脂质家族的一员,被称为花生四烯酸。血栓素因其在血凝块形成(血栓形成)中的作用而得名。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
• 参考文献:

  [1]. Jantine E Bakema, et al. Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs. J Immunol. 2015 Feb 15;194(4):1856-66.

血栓素B1物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 577.1±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₆O₆
• 分子量: 372.496
• 闪点: 196.6±23.6 °C
• 精确质量: 372.251190
• PSA: 107.22000
• LogP: 2.49
• 蒸汽压: 0.0±3.6 mmHg at 25°C
• 折射率: 1.547

血栓素B1靶点实验

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实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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血栓素B1英文别名

• (9β,13E,15S)-9,11,15-Trihydroxythrombox-13-en-1-oic acid