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2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide

更新时间:2025-08-24 22:55:03

2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide结构式
2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide结构式
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常用名 2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide 英文名 2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide
CAS号 65267-04-1 分子量 208.60300
密度 1.58g/cm3 沸点 N/A
分子式 C5H9ClN4O3 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 2-[[2-chloroethyl(nitroso)carbamoyl]amino]acetamide
英文别名 更多

 物理化学性质

密度 1.58g/cm3
分子式 C5H9ClN4O3
分子量 208.60300
精确质量 208.03600
PSA 104.86000
LogP 0.49470
InChIKey BESOTRXDCHQLBP-UHFFFAOYSA-N
SMILES NC(=O)CNC(=O)N(CCCl)N=O
折射率 1.597

 毒性和生态

 合成线路

~40%

2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide结构式

2-[(2-chloroeth...

65267-04-1

文献:Eisenbrand; Gerhard Patent: US4150146 A1, 1979 ;

~73%

2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide结构式

2-[(2-chloroeth...

65267-04-1

文献:Suami; Kato; Takino; Hisamatsu Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 829 - 832

~51%

2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide结构式

2-[(2-chloroeth...

65267-04-1

文献:Sosnovsky; Gnewuch Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 7 p. 989 - 998

 靶点实验

查看更多实验

实验名称:Tested for Maximal effective dose against mouse leukemia L1210 cells
来源:ChEMBL
靶标:L1210
External Id:CHEMBL704270
实验名称:Tested for Number of 60 days survivors per 5 treated mice against mouse leukemia L121...
来源:ChEMBL
靶标:L1210
External Id:CHEMBL707476
实验名称:Tested for the toxicity after ip administration in SLC-BDF1 male mice
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL728075
实验名称:Tested in vitro for Half- life period of the compound
来源:ChEMBL
靶标:N/A
External Id:CHEMBL642546
实验名称:Tested for the toxicity after iv administration in SLC-BDF1 male mice
来源:ChEMBL
靶标:Mus musculus
External Id:CHEMBL728076
实验名称:Tested for Percent increase in life span against mouse leukemia L1210 cells
来源:ChEMBL
靶标:L1210
External Id:CHEMBL704538
实验名称:Tested for Mean survival days against mouse leukemia L1210 cells
来源:ChEMBL
靶标:L1210
External Id:CHEMBL704086
实验名称:Tested for ratio of maximal effective dose/the dose which gives 30% ILS against mouse...
来源:ChEMBL
靶标:L1210
External Id:CHEMBL705258
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 英文别名

1-(Carbamoylmethyl)-3-(2-chloroethyl)-3-nitrosourea
Urea,1-(carbamoylmethyl)-3-(2-chloroethyl)-3-nitroso
N-<N'-(2-chloroethyl)-N'-nitrosocarbamoyl>glycinamide
2-(3-(2-chloroethyl))-3-nitrosoureido acetamide
n2-[(2-chloroethyl)(nitroso)carbamoyl]glycinamide
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