石榴皮鞣素

• 常用名: 石榴皮鞣素
• 英文名: punicalin
• CAS号: 65995-64-4
• 分子量: 782.525
• 密度: 2.1±0.1 g/cm3
• 沸点: 1559.6±65.0 °C at 760 mmHg
• 分子式: C₃₄H₂₂O₂₂
• 熔点: N/A
• 闪点: 484.7±27.8 °C

石榴皮鞣素用途

Punicalin 是一种可水解的单宁,可从 Punica granatum L. 或 Terminalia catappa L. 的叶子中分离。Punicalin 是一种抗乙型肝炎病毒 (HBV) 药物,具有抗炎活性。

石榴皮鞣素名称

• 中文名: 石榴皮鞣素
• 英文名: Punicalin
• 中文别名: 安石榴磷 | 安石榴林

石榴皮鞣素生物活性

• 描述: Punicalin 是一种可水解的单宁,可从 Punica granatum L. 或 Terminalia catappa L. 的叶子中分离。Punicalin 是一种抗乙型肝炎病毒 (HBV) 药物,具有抗炎活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> HBV
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6.

  [2]. Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107.

石榴皮鞣素物理化学性质

• 密度: 2.1±0.1 g/cm3
• 沸点: 1559.6±65.0 °C at 760 mmHg
• 分子式: C₃₄H₂₂O₂₂
• 分子量: 782.525
• 闪点: 484.7±27.8 °C
• 精确质量: 782.060242
• PSA: 385.24000
• LogP: 1.24
• InChIKey: IQHIEHIKNWLKFB-UHFFFAOYSA-N
• SMILES: O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.872
• 储存条件: -20°C

石榴皮鞣素安全信息

• 危险品运输编码: NONH for all modes of transport

石榴皮鞣素靶点实验

查看更多实验

实验名称：Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition ... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL964368

实验名称：Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition ... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL964363

实验名称：Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition ... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL964364

实验名称：Inhibition of HIV-reverse transcriptase in cell culture assay; No data 来源：ChEMBL 靶标：Reverse transcriptase/RNaseH External Id：CHEMBL687081

实验名称：Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition ... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL964370

实验名称：Cytotoxicity against human PRMI7951 cells by tetrazolium salt-based colorimetric assa... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL941398

实验名称：Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL941400

实验名称：Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay 来源：ChEMBL 靶标：KB External Id：CHEMBL941399

实验名称：Compound was tested for anti-HIV activity in cell culture assay; active anti HIV agen... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL688791

实验名称：Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1008468

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石榴皮鞣素英文别名

• punicalin
• (10S,11R,12R,15R)-3,4,5,11,12,13,21,22,23,26,27,38,39-Tridecahydroxy-9,14,17,29,36-pentaoxaoctacyclo[29.8.0.0.0.0.0.0.0]nonatriaconta-1(39),2,4,6,19,21,23,25,27 ,31,33,37-dodecaene-8,18,30,35-tetrone
• gn-30