CZL55

• 常用名: CZL55
• 英文名: CZL55
• CAS号: 667408-87-9
• 分子量: 386.40
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₂N₂O₆
• 熔点: N/A
• 闪点: N/A

CZL55用途

CZL55是一种半胱氨酸蛋白酶-1抑制剂,其IC50值为24nM。CZL55可用于热性惊厥(FS)的研究[1]。

CZL55名称

• 英文名: CZL55

CZL55生物活性

• 描述: CZL55是一种半胱氨酸蛋白酶-1抑制剂,其IC50值为24nM。CZL55可用于热性惊厥(FS)的研究[1]。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 胱天蛋白酶
  研究领域 >> 炎症/免疫
• 靶点实验:

  Caspase-1:24 nM (IC50)

• 参考文献:

  [1]. Tang Y, et al. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177(15):3519-3534.

CZL55物理化学性质

• 分子式: C₂₀H₂₂N₂O₆
• 分子量: 386.40
• InChIKey: IXPHIUQELSUDNK-UHFFFAOYSA-N
• SMILES: COc1ccc(NC(=O)c2cccc(NC(=O)CCCC(=O)O)c2)c(OC)c1

CZL55靶点实验

查看更多实验

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

共3条，当前第1页，共1页

1