(R)-5-Hydroxy-7-(4-hydroxy- 3-methoxyphenyl)-1-phenylheptan-3-one

• 常用名: (R)-5-Hydroxy-7-(4-hydroxy- 3-methoxyphenyl)-1-phenylheptan-3-one
• 英文名: (R)-5-Hydroxy-7-(4-hydroxy- 3-methoxyphenyl)-1-phenylheptan-3-one
• CAS号: 68622-73-1
• 分子量: 328.40200
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₄O₄
• 熔点: N/A
• 闪点: N/A

用途

Antiviral agent 41 (compound 5) 是从铁皮蒿中分离的二芳基七烷类化合物,在体外对流感病毒表现出潜在的抗病毒活性

名称

• 英文名: (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone

生物活性

• 描述: Antiviral agent 41 (compound 5) 是从铁皮蒿中分离的二芳基七烷类化合物,在体外对流感病毒表现出潜在的抗病毒活性
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 参考文献:

  [1]. Sawamura R, et al. Antiviral activities of diarylheptanoids against influenza virus in vitro. J Nat Med. 2010 Jan;64(1):117-20.

物理化学性质

• 分子式: C₂₀H₂₄O₄
• 分子量: 328.40200
• 精确质量: 328.16700
• PSA: 66.76000
• LogP: 3.28630
• InChIKey: JHJPDDBIHSFERA-GOSISDBHSA-N
• SMILES: COc1cc(CCC(O)CC(=O)CCc2ccccc2)ccc1O

靶点实验

查看更多实验

实验名称：Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells at 100 uM ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1044223

实验名称：Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells at 10 uM a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1044221

实验名称：Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells at 30 uM a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1044222

实验名称：Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells at 1 uM af... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1044219

实验名称：Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells at 3 uM af... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1044220

实验名称：Inhibition of mushroom tyrosinase at 1 uM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL1044231

实验名称：Inhibition of mushroom tyrosinase at 3 uM 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL1044232

实验名称：Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as ce... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1044229

实验名称：Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as ce... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1044227

实验名称：Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as ce... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1044228

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