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G43

更新时间:2026-06-30 21:33:37

G43结构式
G43结构式
品牌特惠专场
常用名 G43 英文名 G43
CAS号 690693-02-8 分子量 341.34
密度 N/A 沸点 N/A
分子式 C16H11N3O4S 熔点 N/A
MSDS N/A 闪点 N/A

 G43用途


G43 是一种有效的选择性 glucosyltransferase 抑制剂,对 GtfB 和 GtfC 的Kd 值分别为3.7 μM和46.9 nM。G43 在体内外具有抗变形链球菌 (S. mutans) 的作用,可用于龋齿研究。

 G43名称

英文名 G43

 G43生物活性

描述 G43 是一种有效的选择性 glucosyltransferase 抑制剂,对 GtfB 和 GtfC 的Kd 值分别为3.7 μM和46.9 nM。G43 在体内外具有抗变形链球菌 (S. mutans) 的作用,可用于龋齿研究。
相关类别
参考文献

[1]. Zhang Q, et al. Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence. Sci Rep. 2017;7(1):5974.  

[2]. Scaffa PMC, et al. The potential use of glycosyl-transferase inhibitors for targeted reduction of S. mutans biofilms in dental materials. Sci Rep. 2023;13(1):11889.  

 G43物理化学性质

分子式 C16H11N3O4S
分子量 341.34
InChIKey BTTXJIMSRRTAQM-UHFFFAOYSA-N
SMILES NC(=O)c1ccccc1NC(=O)c1cc2cc([N+](=O)[O-])ccc2s1

 G43靶点实验

查看更多实验

实验名称:Bactericidal activity against Streptococcus mutans UA159 assessed as reduction in bac...
来源:ChEMBL
靶标:Streptococcus mutans
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靶标:N/A
External Id:FATTTLab-Algae-Lipid
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来源:ChEMBL
靶标:Streptococcus sanguinis
External Id:CHEMBL4679606
实验名称:Bactericidal activity against Streptococcus gordonii DL1 assessed as reduction in bac...
来源:ChEMBL
靶标:Streptococcus gordonii
External Id:CHEMBL4679605
实验名称:Antibiofilm activity against Streptococcus mutans UA159 assessed as inhibition of bio...
来源:ChEMBL
靶标:Streptococcus mutans
External Id:CHEMBL4679608
实验名称:Solubility of compound in water
来源:ChEMBL
靶标:N/A
External Id:CHEMBL4679607
实验名称:Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat a...
来源:ChEMBL
靶标:Streptococcus mutans
External Id:CHEMBL4679596
实验名称:Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat a...
来源:ChEMBL
靶标:Streptococcus mutans
External Id:CHEMBL4679595
实验名称:Inhibition of GtfD in Streptococcus mutans UA159 assessed as reduction in glucans lev...
来源:ChEMBL
靶标:Glucosyltransferase-S
External Id:CHEMBL4679598
实验名称:Antibiofilm activity against Streptococcus mutans UA159 infected in Fischer 344 rat a...
来源:ChEMBL
靶标:Streptococcus mutans
External Id:CHEMBL4679597
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