Glucocorticoids receptor agonist 1

• 常用名: Glucocorticoids receptor agonist 1
• 英文名: Glucocorticoids receptor agonist 1
• CAS号: 694526-54-0
• 分子量: 326.41
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃FN₂O
• 熔点: N/A
• 闪点: N/A

Glucocorticoids receptor agonist 1用途

糖皮质激素受体激动剂1是一种有效的抗炎、芳基吡唑类糖皮质激素受体激动剂,不会损害胰岛素分泌。

Glucocorticoids receptor agonist 1名称

• 英文名: Glucocorticoids receptor agonist 1

Glucocorticoids receptor agonist 1生物活性

• 描述: 糖皮质激素受体激动剂1是一种有效的抗炎、芳基吡唑类糖皮质激素受体激动剂,不会损害胰岛素分泌。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 糖皮质激素受体
• 参考文献:

  [1]. Kennedy BJ, et al. Potent Anti-Inflammatory, Arylpyrazole-Based Glucocorticoid Receptor Agonists That Do Not Impair Insulin Secretion. ACS Med Chem Lett. 2021 Sep 15;12(10):1568-1577.

Glucocorticoids receptor agonist 1物理化学性质

• 分子式: C₂₀H₂₃FN₂O
• 分子量: 326.41
• InChIKey: GZUNIDQZQNDLTI-VIZZQPHQSA-N
• SMILES: CC(O)C1CCCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C

Glucocorticoids receptor agonist 1靶点实验

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实验名称：Ability to induce human IL-6 assay in A549 lung carcinoma cell line. 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL620387

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL5126495

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL4840206

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL5126491

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL4840205

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL5126492

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL4840204

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL5126493

实验名称：Ability to induce mouse macrophage IL-6 assay in peritoneal exudate cells harvested b... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL733381

实验名称：Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected wit... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL4840203

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