Sirtuin modulator 3

• 常用名: Sirtuin modulator 3
• 英文名: Sirtuin modulator 3
• CAS号: 708995-11-3
• 分子量: 417.5
• 密度: 1.2±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₄H₂₃N₃O₄
• 熔点: N/A
• 闪点: N/A

Sirtuin modulator 3用途

Sirtuin调节剂3(化合物129)是一种N-苯基苯甲酰胺衍生物,用作Sirtuin调节剂[1]。

Sirtuin modulator 3名称

• 英文名: WAY-272277

Sirtuin modulator 3生物活性

• 描述: Sirtuin调节剂3(化合物129)是一种N-苯基苯甲酰胺衍生物,用作Sirtuin调节剂[1]。
• 相关类别:
  信号通路 >> 表观遗传学 >> 抗衰老酶
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 抗衰老酶
  研究领域 >> 炎症/免疫
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Milburn Michael, et al. Preparation of N-phenyl benzamide derivatives as sirtuin modulators: World Intellectual Property Organization, WO2006094236[P]. 2006-09-08.

Sirtuin modulator 3物理化学性质

• 密度: 1.2±0.1 g/cm3
• 分子式: C₂₄H₂₃N₃O₄
• 分子量: 417.5
• 精确质量: 417.168854
• LogP: 4.27
• InChIKey: ZCNAQCKPWWPHDY-UHFFFAOYSA-N
• SMILES: COc1cc(C(=O)Nc2cccc(-c3cn4ccc(C)cc4n3)c2)cc(OC)c1OC
• 折射率: 1.611
• 储存条件: -80℃储存

Sirtuin modulator 3靶点实验

查看更多实验

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Glucose transporter External Id：CHEMBL3436044

实验名称：Biochemical screen of P. falciparum CDPK1 来源：1187 靶标：Calcium-Dependent Protein Kinase 1 (CDPK1) External Id：PfalCDPK1

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Solute carrier family 2, facilitated glucose transporter member 1 External Id：CHEMBL3436042

实验名称：Biochemical screen of P. falciparum PK7 来源：1187 靶标：Protein Kinase 7 (PK7) External Id：PfalPK7

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Hexose transporter 1 External Id：CHEMBL3436043

实验名称：Biochemical screen of P. falciparum PK6 来源：1187 靶标：Protein Kinase 6 (PK6) External Id：PfalPK6

实验名称：Biochemical screen of P. falciparum MAPK2 来源：1187 靶标：mitogen-activated protein kinase 2 (MAP2 or MAPK2) External Id：PfalMAPK2

实验名称：Biochemical screen of P. falciparum CDPK4 来源：1187 靶标：Calcium-Dependent Protein Kinase 4 (CDPK4) External Id：PfalCDPK4

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

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Sirtuin modulator 3英文别名

• TCMDC-125384
• 3,4,5-Trimethoxy-N-[3-(7-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide