(S)-3-羟基苯甘氨酸

• 常用名: (S)-3-羟基苯甘氨酸
• 英文名: oxfenicine
• CAS号: 71301-82-1
• 分子量: 167.162
• 密度: 1.4±0.1 g/cm3
• 沸点: 382.6±32.0 °C at 760 mmHg
• 分子式: C₈H₉NO₃
• 熔点: N/A
• 闪点: 185.2±25.1 °C

(S)-3-羟基苯甘氨酸用途

(S) -3-羟基苯基甘氨酸((S)-3HPG)是一种有效的mGluR1激动剂,对mGlu2或mGlu4[1]没有作用。

(S)-3-羟基苯甘氨酸名称

• 中文名: (S)-3-羟基苯基甘氨酸
• 英文名: (s)-3-hydroxyphenylglycine

(S)-3-羟基苯甘氨酸生物活性

• 描述: (S) -3-羟基苯基甘氨酸((S)-3HPG)是一种有效的mGluR1激动剂,对mGlu2或mGlu4[1]没有作用。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 谷氨酸受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Y Hayashi, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7.

  [2]. Birse EF, et al. Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience. 1993 Feb;52(3):481-8.

(S)-3-羟基苯甘氨酸物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 382.6±32.0 °C at 760 mmHg
• 分子式: C₈H₉NO₃
• 分子量: 167.162
• 闪点: 185.2±25.1 °C
• 精确质量: 167.058243
• PSA: 83.55000
• LogP: 0.20
• InChIKey: DQLYTFPAEVJTFM-ZETCQYMHSA-N
• SMILES: NC(C(=O)O)c1cccc(O)c1
• 外观性状: 固体
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.633
• 储存条件: 2-8°C， 密封， 干燥

(S)-3-羟基苯甘氨酸靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：Inhibition of ASCT2 mediated [3H]-D-serine uptake in rat hippocampal astrocytes at 1 ... 来源：ChEMBL 靶标：Amino acid transporter External Id：CHEMBL3992321

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E... 来源：NCGC External Id：epac2-activator-v2

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4... 来源：NCGC External Id：epac2-inhibitor-v2

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：qHTS for Inhibitors of Polymerase Kappa 来源：NCGC 靶标：DNA polymerase kappa [Homo sapiens] External Id：PolK100

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(S)-3-羟基苯甘氨酸英文别名

• (2S)-Amino(3-hydroxyphenyl)acetic acid
• (S)-amino-(3-hydroxyphenyl)acetic acid
• (2S)-(+)-2-(3-Hydroxyphenyl)glycin
• (+)-o-fluorophenylglycine
• oxfenicine
• 2-(2-FLUOROPHENYL)GLYCINE
• (aS)-a-Amino-4-hydroxybenzeneacetic Acid
• (2S)-amino(3-hydroxyphenyl)ethanoic acid
• (S)-2-(3-Hydroxyphenyl)glycine
• (2S)-Amino(4-hydroxyphenyl)acetic acid
• (S)-a-Amino-4-hydroxybenzeneacetic Acid
• (S)-AMINO-(2-FLUORO-PHENYL)-ACETIC ACID
• Pyrrolidinedithiocarbamate ammonium
• S-3-hydroxyphenylglycine
• (S)-2-amino-2-(2-fluorophenyl)acetic acid
• (2S)-amino(4-hydroxyphenyl)ethanoic acid