哌啶-4-磺酸

• 常用名: 哌啶-4-磺酸
• 英文名: 4-BROMO-BENZENESULFONIC ACID
• CAS号: 72450-62-5
• 分子量: 165.21
• 密度: 1.39g/cm3
• 沸点: N/A
• 分子式: C₅H₁₁NO₃S
• 熔点: > 300 °C
• 闪点: N/A

哌啶-4-磺酸用途

Piperidine-4-sulfonic acid 是一种有效的 GABA 激动剂,抑制 H-GABA 的结合,IC50 为 0.034 μM。

哌啶-4-磺酸名称

• 中文名: 哌啶-4-磺酸
• 英文名: piperidine-4-sulfonic acid

哌啶-4-磺酸生物活性

• 描述: Piperidine-4-sulfonic acid 是一种有效的 GABA 激动剂,抑制 H-GABA 的结合,IC50 为 0.034 μM。
• 相关类别:
  信号通路 >> 其他 >> 其他
  信号通路 >> 跨膜转运 >> GABA受体
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> GABA受体
• 靶点实验:

  IC50: 0.034 μM (the binding of H-GABA)[1]

• 参考文献:

  [1]. POVL KROGSGAARD-LARSEN, et al. Pharmacological Studies of Interactions Between Benzodiazepines and GABA Receptors. Brain Research Rullrrin. 1980, 5(2):867-872.

  [2]. Krogsgaard-Larsen P, Arnt J. Pharmacological studies of interactions between benzodiazepines and GABA receptors. Brain Research Bulletin, 1980, 5: 867-872.

哌啶-4-磺酸物理化学性质

• 密度: 1.39g/cm3
• 熔点: > 300 °C
• 分子式: C₅H₁₁NO₃S
• 分子量: 165.21
• 精确质量: 165.04600
• PSA: 74.78000
• LogP: 1.03580
• InChIKey: UGBJGGRINDTHIH-UHFFFAOYSA-N
• SMILES: O=S(=O)(O)C1CCNCC1
• 外观性状: 白色固体
• 折射率: 1.537
• 储存条件: 室温

哌啶-4-磺酸安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933399090

哌啶-4-磺酸海关

• 海关编码: 2933399090
• 中文概述: 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

哌啶-4-磺酸靶点实验

查看更多实验

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1266185

实验名称：Maximal response relative to Gamma-aminobutyric acid A against human Gamma-aminobutyr... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-2 External Id：CHEMBL683016

实验名称：Human GABAA receptor alpha5 subunit (GABAA receptors) 来源：IUPHAR-DB 靶标：GABAA receptor alpha5 subunit (GABAA receptors) [Homo sapiens] External Id：408_Human

实验名称：Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-ga... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-6 External Id：CHEMBL682418

实验名称：Human GABAA receptor alpha1 subunit (GABAA receptors) 来源：IUPHAR-DB 靶标：GABAA receptor alpha1 subunit (GABAA receptors) [Homo sapiens] External Id：404_Human

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Human GABAA receptor rho3 subunit (GABAA receptors) 来源：IUPHAR-DB 靶标：GABAA receptor rho3 subunit (GABAA receptors) [Homo sapiens] External Id：422_Human

实验名称：The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre... 来源：11924 靶标：N/A External Id：CGM data for Cell Systems paper Dec 2015

实验名称：96-well format Chlamydomonas reinhardtii Algae Gravitaxis Assay to measure the differ... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：N/A External Id：MH081217, Chlamydomonas reinhardtii Gravitaxis Assay to Identify Small Molecule Inhibitors of Cilia.

实验名称：Maximal response relative to Gamma-aminobutyric acid A against human Gamma-aminobutyr... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL681091

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哌啶-4-磺酸英文别名

• C5H11NO3S
• P4S
• Lopac-P-9159
• 4-Piperidinesulfonic acid
• Piperidine-4-sulphonic acid