ALK抑制剂1

• 常用名: ALK抑制剂1
• 英文名: ALK inhibitor 1
• CAS号: 761436-81-1
• 分子量: 562.48300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₈BrN₇O₃S
• 熔点: N/A
• 闪点: N/A

ALK抑制剂1用途

ALK抑制剂1是新型ALK选择性抑制剂。

ALK抑制剂1名称

• 中文名: ALK抑制剂1
• 英文名: 2-[[5-bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

ALK抑制剂1生物活性

• 描述: ALK抑制剂1是新型ALK选择性抑制剂。
• 相关类别:
  信号通路 >> 蛋白酪氨酸激酶 >> ALK
  研究领域 >> 癌症
• 参考文献:

  [1]. A Dose Finding Study With Oral LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase (ALK).

ALK抑制剂1物理化学性质

• 分子式: C₂₃H₂₈BrN₇O₃S
• 分子量: 562.48300
• 精确质量: 561.11600
• PSA: 123.33000
• LogP: 4.36430
• InChIKey: FTSDLONCFCQDGA-UHFFFAOYSA-N
• SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2OC)ncc1Br
• 储存条件: 2-8℃

ALK抑制剂1靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Confirmatory qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2) 来源：NCGC External Id：TRND-GPT2-f1-with-DTT

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

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ALK抑制剂1英文别名

• ALK inhibitor 1
• CS-0788