seravschanin

• 常用名: seravschanin
• 英文名: seravschanin
• CAS号: 77331-76-1
• 分子量: 374.38
• 密度: 1.3±0.1 g/cm3
• 沸点: 465.7±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂O₇
• 熔点: 166-167℃ (ethanol )
• 闪点: 202.5±28.8 °C

seravschanin用途

Hyuganin D(Isobocconin)是一种香豆素(HY-N0709)成分,可显著抑制LPS(HY-D1056)诱导的小鼠腹腔巨噬细胞中NO的产生[1]。

seravschanin名称

• 英文名: (9R,10R)-9-acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl isobutyrate

seravschanin生物活性

• 描述: Hyuganin D(Isobocconin)是一种香豆素(HY-N0709)成分,可显著抑制LPS(HY-D1056)诱导的小鼠腹腔巨噬细胞中NO的产生[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Yoshikawa M, et al. Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg Med Chem. 2006 Jan 15;14(2):456-63.

seravschanin物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 465.7±45.0 °C at 760 mmHg
• 熔点: 166-167℃ (ethanol )
• 分子式: C₂₀H₂₂O₇
• 分子量: 374.38
• 闪点: 202.5±28.8 °C
• 精确质量: 374.136566
• PSA: 92.04000
• LogP: 3.37
• InChIKey: BUTUNJHEBGRWGK-UHFFFAOYSA-N
• SMILES: CC(=O)OC1C(OC(=O)C(C)C)c2c(ccc3ccc(=O)oc23)OC1(C)C
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.564
• 储存条件: 2-8℃，干燥，密闭

seravschanin安全信息

• 危害码 (欧洲): Xi

seravschanin靶点实验

查看更多实验

实验名称：Inhibitory activity against LPS-induced NO production in mouse peritoneal macrophages... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL741599

实验名称：Binding affinity to spinach calmodulin assessed as modification of electrophoretic mo... 来源：ChEMBL 靶标：Calmodulin External Id：CHEMBL1006904

实验名称：Binding affinity to bovine brain calmodulin assessed as modification of electrophoret... 来源：ChEMBL 靶标：Calmodulin External Id：CHEMBL1006903

实验名称：Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL784307

实验名称：Phytotoxicity against Echinochloa crus-galli assessed as inhibition of radicle elonga... 来源：ChEMBL 靶标：Echinochloa crus-galli External Id：CHEMBL966027

实验名称：Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes at 100 uM 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL787893

实验名称：Phytotoxicity against Amaranthus hypochondriacus assessed as inhibition of radicle el... 来源：ChEMBL 靶标：Amaranthus hypochondriacus External Id：CHEMBL966026

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seravschanin英文别名

• Propanoic acid, 2-methyl-, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester
• (9R,10R)-9-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 2-methylpropanoate
• (9R,10R)-9-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 2-methylpropanoate