Streptazolin

• 常用名: Streptazolin
• 英文名: Streptazolin
• CAS号: 80152-07-4
• 分子量: 207.226
• 密度: 1.4±0.1 g/cm3
• 沸点: 490.2±45.0 °C at 760 mmHg
• 分子式: C₁₁H₁₃NO₃
• 熔点: N/A
• 闪点: 250.3±28.7 °C

Streptazolin用途

Streptazolin是一种抗生素。Streptazolin在体外增加巨噬细胞对细菌的杀灭和免疫刺激细胞因子的分泌。Streptazolin通过PI3K信号通路刺激巨噬细胞NF-κB通路[1][2]。

Streptazolin名称

• 英文名: Streptazolin

Streptazolin生物活性

• 描述: Streptazolin是一种抗生素。Streptazolin在体外增加巨噬细胞对细菌的杀灭和免疫刺激细胞因子的分泌。Streptazolin通过PI3K信号通路刺激巨噬细胞NF-κB通路[1][2]。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Groenhagen U, et al. Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5. Beilstein J Org Chem. 2014;10:1421-1432. Published 2014 Jun 24.

  [2]. Perry JA, et al. A macrophage-stimulating compound from a screen of microbial natural products. J Antibiot (Tokyo). 2015;68(1):40-46.

Streptazolin物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 490.2±45.0 °C at 760 mmHg
• 分子式: C₁₁H₁₃NO₃
• 分子量: 207.226
• 闪点: 250.3±28.7 °C
• 精确质量: 207.089539
• LogP: 0.76
• InChIKey: OJIUACOQFBQCDF-IKXJTIOISA-N
• SMILES: CC=C1C2=CCCN3C(=O)OC(C1O)C23
• 蒸汽压: 0.0±2.8 mmHg at 25°C
• 折射率: 1.632

Streptazolin靶点实验

查看更多实验

实验名称：USP8 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 8 External Id：USP8 FAST DUB HTS Primary

实验名称：USP17 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 17 like family member 5 External Id：USP17 FAST DUB HTS Primary

实验名称：USP7 deubiquitinase inhibition: Primary qHTS 来源：24642 靶标：ubiquitin specific peptidase 7 External Id：USP7 FAST DUB HTS Primary

实验名称：Cytotoxicity against human Kato3 cells at 50 umol/L 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL966416

实验名称：Cytotoxicity against human MCF7 cells at 50 umol/L 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL966417

实验名称：Cytotoxicity against human HMO2 cells at 50 umol/L 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL966411

实验名称：USP30 deubiquitinase inhibition: Dose-response Confirmation 来源：24642 靶标：ubiquitin specific peptidase 30 External Id：USP30 FAST DUB HTS Confirmation

实验名称：USP17 deubiquitinase inhibition: Dose-response Confirmation 来源：24642 靶标：ubiquitin specific peptidase 17 like family member 5 External Id：USP17 FAST DUB HTS Confirmation

实验名称：USP28 deubiquitinase inhibition: Dose-response Confirmation 来源：24642 靶标：ubiquitin specific peptidase 28 External Id：USP28 FAST DUB HTS Confirmation

实验名称：OTUD3 deubiquitinase inhibition: Dose-response Confirmation 来源：24642 靶标：OTU deubiquitinase 3 External Id：OTUD3 FAST DUB HTS Confirmation

共18条，当前第1页，共2页

1

2

Streptazolin英文别名

• (+)-streptazolin
• streptazolin
• (2aS,3S,4Z,7bS)-4-Ethylidene-3-hydroxy-2a,3,4,6,7,7b-hexahydro-2-oxa-7a-azacyclopenta[cd]inden-1-one