Rupestonic acid

• 常用名: Rupestonic acid
• 英文名: Rupestonic acid
• CAS号: 83161-56-2
• 分子量: 248.31700
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₂₀O₃
• 熔点: N/A
• 闪点: N/A

Rupestonic acid用途

Rupestonic acid 是从 Artemisia rupestris L. 中分离出的一种含多官能团的倍半萜类化合物。Rupestonic acid 能抑制流感病毒 (influenza virus)。

Rupestonic acid名称

• 英文名: 2-(3,8-dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydroazulen-5-yl)-acrylic acid

Rupestonic acid生物活性

• 描述: Rupestonic acid 是从 Artemisia rupestris L. 中分离出的一种含多官能团的倍半萜类化合物。Rupestonic acid 能抑制流感病毒 (influenza virus)。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 参考文献:

  [1]. Obul M, et al. Structural modification on rupestonic acid leads to highly potent inhibitors against influenza virus. Mol Divers. 2019 Feb;23(1):1-9.

Rupestonic acid物理化学性质

• 分子式: C₁₅H₂₀O₃
• 分子量: 248.31700
• 精确质量: 248.14100
• PSA: 54.37000
• LogP: 2.96890
• InChIKey: ZFHSKBJBODQVBX-AXTRIDKLSA-N
• SMILES: C=C(C(=O)O)C1CCC(C)C2CC(=O)C(C)=C2C1

Rupestonic acid靶点实验

查看更多实验

实验名称：Selectivity index, ratio of TC50 for cytotoxicity against dog MDCK cells to IC50 for ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376260

实验名称：Selectivity index, ratio of TC50 for MDCK cells to IC50 for influenza A virus H3N2 来源：ChEMBL 靶标：N/A External Id：CHEMBL1960700

实验名称：Cytotoxicity against MDCK cells 来源：ChEMBL 靶标：MDCK External Id：CHEMBL1960699

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Small-molecule inhibitors of ST2 (IL1RL1) 来源：20881 靶标：interleukin-1 receptor-like 1 isoform [homo sapiens] External Id：ST2_IL33_Inhibitors_Primary_Screening_77700

实验名称：Cytotoxicity against MDCK cells assessed as reduction in cell viability incubated for... 来源：ChEMBL 靶标：MDCK External Id：CHEMBL4376254

实验名称：Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells pre-incubated for ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3388890

实验名称：Antiviral activity against Influenza A virus H1N1 infected in dog MDCK cells assessed... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL4376255

实验名称：Selectivity index, ratio of TC50 for cytotoxicity against dog MDCK cells to IC50 for ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376256

实验名称：Antiinfluenza activity against influenza A virus H3N2 infected in MDCK cells assessed... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1960696

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Rupestonic acid英文别名

• rupestonic acid
• (+)-3-oxo-1αH,7αH,10αH-guaia-4,11-dien-12-oic acid
• Pechueloic acid
• (+)-pechueloic acid
• 2-((5R,8S,8aS)-3,8-dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydroazulen-5-yl)acrylic acid
• 2-((5R,8S,8aS)-3,8-Dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydro-azulen-5-yl)-acrylic acid