ML-031

• 常用名: ML-031
• 英文名: ML031
• CAS号: 852230-33-2
• 分子量: 324.374
• 密度: 1.2±0.1 g/cm3
• 沸点: 568.8±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₀N₂O₃
• 熔点: N/A
• 闪点: 297.8±30.1 °C

ML-031用途

CYM-5482是一种有效的选择性激动剂鞘氨醇1-磷酸受体2(S1PR2),IC50和EC50分别为1.0和1.03μM。CYM-5482具有研究癌症疾病的潜力【1】。

ML-031名称

• 中文名: ML-031
• 英文名: 1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-2,5-pyrro lidinedione

ML-031生物活性

• 描述: CYM-5482是一种有效的选择性激动剂鞘氨醇1-磷酸受体2(S1PR2),IC50和EC50分别为1.0和1.03μM。CYM-5482具有研究癌症疾病的潜力【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> LPL受体
• 参考文献:

  [1]. Satsu H, et al. A sphingosine 1-phosphate receptor 2 selective allosteric agonist. Bioorg Med Chem. 2013;21(17):5373-5382.

ML-031物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 568.8±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₀N₂O₃
• 分子量: 324.374
• 闪点: 297.8±30.1 °C
• 精确质量: 324.147400
• PSA: 59.38000
• LogP: 1.95
• InChIKey: JRESCQKIRPOOEM-UHFFFAOYSA-N
• SMILES: Cc1cc(C(=O)CN2C(=O)CCC2=O)c(C)n1Cc1ccccc1
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.617
• 储存条件: -20°C，密闭，干燥

ML-031靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

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ML-031英文别名

• 1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-2,5-pyrrolidinedione