Patentiflorin A

• 常用名: Patentiflorin A
• 英文名: Patentiflorin A
• CAS号: 857050-63-6
• 分子量: 526.49
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₆O₁₁
• 熔点: N/A
• 闪点: N/A

Patentiflorin A用途

Patentiflorin A是一种有效的广谱HIV-1抑制剂。Patentiflorin A也抑制HIV耐药菌株[1]。

Patentiflorin A名称

• 英文名: Patentiflorin A

Patentiflorin A生物活性

• 描述: Patentiflorin A是一种有效的广谱HIV-1抑制剂。Patentiflorin A也抑制HIV耐药菌株[1]。
• 相关类别:
  信号通路 >> 抗感染 >> HIV
  研究领域 >> 感染
• 靶点实验:

  HIV-1

• 体外研究: Patentiflorin A对Bal:M-Tropic、89.6:Dual-tropics、SF162:M-topic、Lav显示抑制活性,IC50值为32、31、30、32、108、61和47 nM。04:T-Tropic、HIV-1LAV、HIV-11617-1和HIV-1N119分别[1]。
• 参考文献:

  [1]. Zhang HJ, et al. Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa. J Nat Prod. 2017 Jun 23;80(6):1798-1807.

Patentiflorin A物理化学性质

• 分子式: C₂₇H₂₆O₁₁
• 分子量: 526.49

Patentiflorin A靶点实验

查看更多实验

实验名称：Cytotoxicity against human A549 cells at 19 uM after 48 hrs by CellTiter 96 AQueous o... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4191600

实验名称：Antiviral activity against HIV1/VSV-G pseudovirus infected in human A549 cells assess... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL4191609

实验名称：Antiviral activity against HIV1/VSV-G pseudovirus infected in human A549 cells assess... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL4191611

实验名称：Cell cycle arrest in human HL60 cells assessed as accumulation at S phase at 10 uM af... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1931138

实验名称：Antiviral activity against recombinant Ebola virus Mayinga expressing GFP infected in... 来源：ChEMBL 靶标：Ebolavirus External Id：CHEMBL5585459

实验名称：Cell cycle arrest in human HL60 cells assessed as accumulation at G2/M phase at 10 uM... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1931140

实验名称：Selectivity index, ratio of CC50 for HEK293 cells to EC50 for recombinant Ebola virus... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5585460

实验名称：Cell cycle arrest in human HL60 cells assessed as accumulation at G2/M phase at 1 uM ... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL1931139

实验名称：Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL5585461

实验名称：Cell cycle arrest in human HCT116 cells assessed as accumulation at G0/G1 phase at 1 ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL1931142

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