Mirodenafil dihydrochloride

• 常用名: Mirodenafil dihydrochloride
• 英文名: Mirodenafil (dihydrochloride)
• CAS号: 862189-96-6
• 分子量: 604.58900
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₉Cl₂N₅O₅S
• 熔点: N/A
• 闪点: N/A

Mirodenafil dihydrochloride用途

Mirodenafil(SK3530)双盐酸盐是磷酸二酯酶5(PDE-5)抑制剂,可作用于勃起功能紊乱。

Mirodenafil dihydrochloride名称

• 中文名: Mirodenafil dihydrochloride
• 英文名: 5-Ethyl-2-(5-{[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl}-2-propo xyphenyl)-7-propyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one d ihydrochloride

Mirodenafil dihydrochloride生物活性

• 描述: Mirodenafil(SK3530)双盐酸盐是磷酸二酯酶5(PDE-5)抑制剂,可作用于勃起功能紊乱。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 磷酸二酯酶(PDE)
  研究领域 >> 其他
• 参考文献:

  [1]. Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment of erectile dysfunction. J Sex Med, 2008. 5(11): p. 2672-80.

  [2]. Kim, B.H., et al., Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther, 2009. 31(6): p. 1234-43.

  [3]. Shin, K.H., et al., The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study. Clin Ther, 2009. 31(12): p. 3009-20.

Mirodenafil dihydrochloride物理化学性质

• 分子式: C₂₆H₃₉Cl₂N₅O₅S
• 分子量: 604.58900
• 精确质量: 603.20500
• PSA: 129.40000
• LogP: 5.42430
• InChIKey: CKPHITUXXABKDL-UHFFFAOYSA-N
• SMILES: CCCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1-c1nc2c(CCC)cn(CC)c2c(=O)[nH]1.Cl.Cl
• 储存条件: 2-8℃

Mirodenafil dihydrochloride英文别名

• Mirodenafil (dihydrochloride)