PXYC2

• 常用名: PXYC2
• 英文名: PXYC2
• CAS号: 865101-22-0
• 分子量: 226.21
• 密度: N/A
• 沸点: N/A
• 分子式: C₇H₆N₄O₃S
• 熔点: N/A
• 闪点: N/A

PXYC2用途

PXYC2是一种核糖体蛋白S1(RpsA)拮抗剂,RpsA-CTD和RpsA-CTDΔ438A的Kds分别为6.35和5.11μM。RpsA在结核分枝杆菌(Mtb)的转译过程中起着重要作用[1]。

PXYC2名称

• 英文名: PXYC2

PXYC2生物活性

• 描述: PXYC2是一种核糖体蛋白S1(RpsA)拮抗剂,RpsA-CTD和RpsA-CTDΔ438A的Kds分别为6.35和5.11μM。RpsA在结核分枝杆菌(Mtb)的转译过程中起着重要作用[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Kd: 6.35 μM (RpsA-CTD), 5.11 μM (RpsA-CTD Δ438A)[1]

• 参考文献:

  [1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis. Eur J Med Chem. 2020 Jun 15;196:112317.

PXYC2物理化学性质

• 分子式: C₇H₆N₄O₃S
• 分子量: 226.21

PXYC2靶点实验

查看更多实验

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768994

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768995

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768992

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768993

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Binding affinity to Mycobacterium tuberculosis 15N-labelled wild type RpsA (280 to 43... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768998

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768996

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768997

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS1303

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