FP0429

• 常用名: FP0429
• 英文名: FP0429
• CAS号: 870860-41-6
• 分子量: 272.21
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₀H₁₂N₂O₇
• 熔点: N/A
• 闪点: N/A

FP0429用途

FP0429 是一种完全 mGlu4 激动剂和部分 mGlu8 激动剂,EC50 值分别为 48.3 μM 和 56.2 μM。

FP0429名称

• 英文名: FP0429

FP0429生物活性

• 描述: FP0429 是一种完全 mGlu4 激动剂和部分 mGlu8 激动剂,EC50 值分别为 48.3 μM 和 56.2 μM。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 谷氨酸受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Schann S, et al. Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4856-60.

FP0429物理化学性质

• 分子式: C₁₀H₁₂N₂O₇
• 分子量: 272.21
• InChIKey: ZALHFQNLXQORTH-FGLATXDZSA-N
• SMILES: NC1(C(=O)O)CC(C(=O)O)N(C(=O)C=CC(=O)O)C1

FP0429靶点实验

查看更多实验

实验名称：Activity at rat mGluR3 receptor measured as intracellular calcium concentration in HE... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 3 External Id：CHEMBL912660

实验名称：Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HE... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 8 External Id：CHEMBL912667

实验名称：Activity against rat mGluR4 receptor measured as intracellular calcium concentration ... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 4 External Id：CHEMBL912668

实验名称：Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HE... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 8 External Id：CHEMBL912669

实验名称：Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HE... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 4 External Id：CHEMBL912670

实验名称：Human mGlu4 receptor (Metabotropic glutamate receptors) 来源：IUPHAR-DB 靶标：mGlu4 receptor (Metabotropic glutamate receptors) [Homo sapiens] External Id：292_Human

实验名称：Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HE... 来源：ChEMBL 靶标：Metabotropic glutamate receptor 4 External Id：CHEMBL912666

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FP0429英文别名

• FP 0429
• FP-0429