Demethylcarolignan E

• 常用名: Demethylcarolignan E
• 英文名: Demethylcarolignan E
• CAS号: 873694-46-3
• 分子量: 716.73
• 密度: 1.3±0.1 g/cm3
• 沸点: 944.4±65.0 °C at 760 mmHg
• 分子式: C₃₉H₄₀O₁₃
• 熔点: N/A
• 闪点: 290.7±27.8 °C

Demethylcarolignan E用途

脱甲基卡洛林酯E是一种苯丙烷酯,可从木槿茎中分离得到。去甲基卡洛林安E对人癌症A549和MCF-7细胞具有细胞毒性(IC50:<10μg/mL)[1]。

Demethylcarolignan E名称

• 英文名: (2S,3S)-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-(2-hydroxy-4-(3-(((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)oxy)propyl)phenoxy)propyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate

Demethylcarolignan E生物活性

• 描述: 脱甲基卡洛林酯E是一种苯丙烷酯,可从木槿茎中分离得到。去甲基卡洛林安E对人癌症A549和MCF-7细胞具有细胞毒性(IC50:<10μg/mL)[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Wu PL, et al. Cytotoxicity of phenylpropanoid esters from the stems of Hibiscus taiwanensis. Bioorg Med Chem. 2004 May 1;12(9):2193-7.

Demethylcarolignan E物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 944.4±65.0 °C at 760 mmHg
• 分子式: C₃₉H₄₀O₁₃
• 分子量: 716.73
• 闪点: 290.7±27.8 °C
• 精确质量: 716.246887
• PSA: 190.67000
• LogP: 3.90
• InChIKey: GSGRJWMOIKUHLN-UHFFFAOYSA-N
• SMILES: COc1cc(C=CC(=O)OCCCc2ccc(OC(COC(=O)C=Cc3ccc(O)c(OC)c3)C(O)c3ccc(O)c(OC)c3)c(O)c2)ccc1O
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.649
• 储存条件: 2-8℃，干燥，密闭

Demethylcarolignan E安全信息

• 危害码 (欧洲): Xi

Demethylcarolignan E靶点实验

查看更多实验

实验名称：Inhibition of Wnt/beta-catenin signaling in HEK293 cells stably transfected with TOP ... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3591882

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实验名称：Cytotoxicity against human Wnt-dependent SW480 cells after 24 hrs by fluorometric mic... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL3591886

实验名称：Cytotoxicity against human Wnt-dependent DLD1 cells after 24 hrs by fluorometric micr... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3591887

实验名称：Cytotoxicity against human HEK293 cells after 24 hrs by fluorometric microculture cyt... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL3591884

实验名称：Cytotoxicity against human Wnt-independent RKO cells after 24 hrs by fluorometric mic... 来源：ChEMBL 靶标：RKO External Id：CHEMBL3591885

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实验名称：Cytotoxicity against human Wnt-dependent HCT116 cells after 24 hrs by fluorometric mi... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL3591888

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Demethylcarolignan E英文别名

• 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 3-[3-hydroxy-4-[[(1S,2S)-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-[[[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]oxy]methyl]ethyl]oxy]phenyl]
• 3-(3-Hydroxy-4-{[(1S,2S)-1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-{[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoyl]oxy}-2-propanyl]oxy}phenyl)propyl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
• Demethylcarolignan E