2-脱甲基硫代秋水仙碱

• 常用名: 2-脱甲基硫代秋水仙碱
• 英文名: Thiocolchicine analog
• CAS号: 87424-26-8
• 分子量: 401.47600
• 密度: 1.33g/cm3
• 沸点: 766.8ºC at 760 mmHg
• 分子式: C₂₁H₂₃NO₅S
• 熔点: 218-220ºC
• 闪点: 417.6ºC

2-脱甲基硫代秋水仙碱名称

• 中文名: 2-脱甲基硫代秋水仙碱
• 英文名: N-[(7S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

2-脱甲基硫代秋水仙碱物理化学性质

• 密度: 1.33g/cm3
• 沸点: 766.8ºC at 760 mmHg
• 熔点: 218-220ºC
• 分子式: C₂₁H₂₃NO₅S
• 分子量: 401.47600
• 闪点: 417.6ºC
• 精确质量: 401.13000
• PSA: 110.16000
• LogP: 3.67280
• InChIKey: OMQLBXIHBJAOIO-HNNXBMFYSA-N
• SMILES: COc1cc2c(c(OC)c1O)-c1ccc(SC)c(=O)cc1C(NC(C)=O)CC2
• 折射率: 1.636

2-脱甲基硫代秋水仙碱毒性和生态

2-脱甲基硫代秋水仙碱靶点实验

查看更多实验

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

实验名称：Lethal dose after the intraperitoneal injection in a group of 10 mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL728031

实验名称：Cytotoxicity against human H9 cells 来源：ChEMBL 靶标：H9 External Id：CHEMBL1019291

实验名称：MED(minimum effective dose) against P388 lymphocytic leukemia in mice; this dose prod... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL879111

实验名称：Antitumor activity against P388 lymphocytic leukemia in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL713637

实验名称：Antiviral activity against HIV1 HTLV-3B in human H9 cells after 3 days by p24 antigen... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL1019290

实验名称：In vitro inhibition of mammalian tubulin polymerization by 50% 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL819249

实验名称：Percentage by which the binding of [3H]colchicine (2.5 uM) to tubulin from calf brain... 来源：ChEMBL 靶标：Tubulin beta-2B chain External Id：CHEMBL815056

实验名称：Percentage inhibition of multi drug resistant KB subclone growth expressing P-glycopr... 来源：ChEMBL 靶标：KB 3-1 External Id：CHEMBL827698

实验名称：Inhibition of tubulin polymerization interacting at the colchicine binding site. 来源：ChEMBL 靶标：Tubulin alpha-1A chain External Id：CHEMBL817769

共26条，当前第1页，共3页

1

2

3

2-脱甲基硫代秋水仙碱英文别名

• N-((S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide
• N-((S)-2-Hydroxy-1,3-dimethoxy-10-methylmercapto-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamid
• 2-Demethyl Thiocolchicine
• COLCHICINE,O(sup 2)-DEMETHYL-10-THIO
• (S)-7-Acetylamino-2-hydroxy-1,3-dimethoxy-10-methylmercapto-6,7-dihydro-5H-benzo[a]heptalen-9-on
• O(sup 2)-Demethyl-10-thiocolchicine