GPR40/FFAR1调制器1

更新时间：2026-07-01 17:52:33

GPR40/FFAR1调制器1结构式	常用名	GPR40/FFAR1调制器1	英文名	GPR40/FFAR1 modulator 1
	CAS号	874755-26-7	分子量	389.41
	密度	N/A	沸点	N/A
	分子式	C₂₁H₁₉N₅O₃	熔点	N/A
	MSDS	N/A	闪点	N/A

GPR40/FFAR1调制器1用途

GPR40/FFAR1 modulator 1 是一种 Gq 偶联游离脂肪酸受体 1 (GPR40/FFAR1) 的激动剂,也是其别构调节剂。

中文名	GPR40/FFAR1调制器1
英文名	GPR40/FFAR1 modulator 1

描述	GPR40/FFAR1 modulator 1 是一种 Gq 偶联游离脂肪酸受体 1 (GPR40/FFAR1) 的激动剂,也是其别构调节剂。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> GPR40 研究领域 >> 代谢疾病
靶点实验	Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)[1].
参考文献	[1]. Lückmann M, et al. Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7123-7128.

分子式	C₂₁H₁₉N₅O₃
分子量	389.41
InChIKey	WCRLDDWRDAIHGO-UHFFFAOYSA-N
SMILES	Cc1ccccc1Nc1nc(N)nc(COc2ccc3c(C)cc(=O)oc3c2)n1
储存条件	-20°C

实验名称：Inhibition of the Burkholderia mallei acyl-homoserine lactone synthase BmaI1
来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：autoinducer synthetase family protein [Burkholderia mallei ATCC 23344]
External Id：HMS1126

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：HCMV UL50
External Id：HMS1262

实验名称：Agonist activity at GPR40 (unknown origin) assessed as maximum efficacy relative to c...
来源：ChEMBL
靶标：Free fatty acid receptor 1
External Id：CHEMBL5216602

实验名称：Positive allosteric modulation of GPR40 (unknown origin) at 100 uM assessed as maximu...
来源：ChEMBL
靶标：Free fatty acid receptor 1
External Id：CHEMBL5216604

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id：HMS979

实验名称：A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：Chain A, Poliovirus Polymerase With Gtp
External Id：HMS750

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