14-去氧鞘蕊酮U

• 常用名: 14-去氧鞘蕊酮U
• 英文名: 14-deoxycoleon
• CAS号: 88664-09-9
• 分子量: 330.42
• 密度: 1.3±0.1 g/cm3
• 沸点: 544.4±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₆O₄
• 熔点: N/A
• 闪点: 297.1±26.6 °C

14-去氧鞘蕊酮U用途

14-脱氧胆酸U是一种天然的枞烷型二萜。14-脱氧胆酸U对肿瘤细胞增殖有抑制作用。14脱氧胆酸U可能是一种用于肺癌研究的有效抗癌先导化合物[1]。

14-去氧鞘蕊酮U名称

• 中文名: 6-羟基丹参酚酮
• 英文名: 14-Deoxycoleon U

14-去氧鞘蕊酮U生物活性

• 描述: 14-脱氧胆酸U是一种天然的枞烷型二萜。14-脱氧胆酸U对肿瘤细胞增殖有抑制作用。14脱氧胆酸U可能是一种用于肺癌研究的有效抗癌先导化合物[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Peng X, et al. 14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma. Onco Targets Ther. 2019;12:5955-5965

14-去氧鞘蕊酮U物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 544.4±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₆O₄
• 分子量: 330.42
• 闪点: 297.1±26.6 °C
• 精确质量: 330.183105
• PSA: 77.76000
• LogP: 5.20
• InChIKey: QDFALZMZLBCVCD-HXUWFJFHSA-N
• SMILES: CC(C)c1cc2c(c(O)c1O)C1(C)CCCC(C)(C)C1=C(O)C2=O
• 外观性状: 黄色粉末
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.612
• 储存条件: 室温

14-去氧鞘蕊酮U安全信息

• 危害码 (欧洲): Xi

14-去氧鞘蕊酮U靶点实验

查看更多实验

实验名称：Cytotoxicity against human BxPC3 cells assessed as growth inhibition by WST-8 assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3095729

实验名称：Cytotoxicity against human PANC1 cells assessed as growth inhibition by WST-8 assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3095730

实验名称：Cytotoxicity against human HL60 cells assessed as growth inhibition by WST-8 assay 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3095731

实验名称：Cytotoxicity against human PC3 cells assessed as growth inhibition by WST-8 assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL3095732

实验名称：Cytotoxicity against human A549 cells assessed as growth inhibition by WST-8 assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL3095733

实验名称：Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 4... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4812858

实验名称：Antibacterial activity against Staphylococcus aureus assessed as growth inhibition at... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3428588

实验名称：Antitumor activity against human HL60 cells at 10'-4 mol/l by MTT assay 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL944242

实验名称：Antibacterial activity against Staphylococcus epidermidis assessed as growth inhibiti... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL3428591

实验名称：Antibacterial activity against Staphylococcus epidermidis assessed as growth inhibiti... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL3428592

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14-去氧鞘蕊酮U英文别名

• 6,11,12-Trihydroxyabieta-5,8(14),9(11),12-tetraen-7-one
• 14-deoxycoleon