麦冬皂苷C

• 常用名: 麦冬皂苷C
• 英文名: Sprengerinin C
• CAS号: 88861-91-0
• 分子量: 855.02
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₄₄H₇₀O₁₆
• 熔点: 262-265℃ (methanol )
• 闪点: N/A

麦冬皂苷C用途

Sprengerinin是一种潜在的血管生成 angiogenesis 抑制剂。Sprengerinin体外抗肿瘤作用 .

麦冬皂苷C名称

• 中文名: 麦冬皂苷 C
• 英文名: (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->4)]-β-D-glucopyranoside

麦冬皂苷C生物活性

• 描述: Sprengerinin是一种潜在的血管生成 angiogenesis 抑制剂。Sprengerinin体外抗肿瘤作用 .
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 靶点实验:

  IC50: angiogenesis[1]

• 参考文献:

  [1]. Ke-Wu Zeng, et al. Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis. Eur J Pharmacol. 2013 Aug 15;714(1-3):261-73.

麦冬皂苷C物理化学性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 262-265℃ (methanol )
• 分子式: C₄₄H₇₀O₁₆
• 分子量: 855.02
• 精确质量: 854.46600
• PSA: 235.68000
• LogP: 6.92
• InChIKey: HSOMTBUZSIVDQK-QYOOOATOSA-N
• SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(OC7OCC(O)C(O)C7O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C
• 外观性状: 粉末
• 折射率: 1.618
• 储存条件: 2-8℃

麦冬皂苷C安全信息

• 危害码 (欧洲): Xi

麦冬皂苷C靶点实验

查看更多实验

实验名称：Antimicrobial activity against Neisseria gonorrhoeae at 64 ug/mL by broth micro dilut... 来源：ChEMBL 靶标：Neisseria gonorrhoeae External Id：CHEMBL1002578

实验名称：Growth inhibition of mouse P388 cells after 48 hrs 来源：ChEMBL 靶标：P388 External Id：CHEMBL1002579

实验名称：Antimicrobial activity against Enterobacter cloacae at 64 ug/mL by broth micro diluti... 来源：ChEMBL 靶标：Enterobacter cloacae External Id：CHEMBL1002576

实验名称：Antimicrobial activity against Stenotrophomonas maltophilia at 64 ug/mL by broth micr... 来源：ChEMBL 靶标：Stenotrophomonas maltophilia External Id：CHEMBL1002577

实验名称：Antimicrobial activity against Enterococcus faecalis at 64 ug/mL by broth micro dilut... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL1002574

实验名称：Antimicrobial activity against Escherichia coli at 64 ug/mL by broth micro dilution a... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL1002575

实验名称：Antimicrobial activity against Micrococcus luteus presque Isle 456 at 64 ug/mL by bro... 来源：ChEMBL 靶标：Micrococcus luteus External Id：CHEMBL1002572

实验名称：Antimicrobial activity against Staphylococcus aureus at 64 ug/mL by broth micro dilut... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1002573

实验名称：Growth inhibition of human KM20L2 cells after 48 hrs 来源：ChEMBL 靶标：KM-20L2 External Id：CHEMBL1002584

实验名称：Growth inhibition of human DU145 cells after 48 hrs 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL1002585

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麦冬皂苷C英文别名

• (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->4)]-β-D-glucopyranoside
• (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)-5-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol