YS-035 hydrochloride

• 常用名: YS-035 hydrochloride
• 英文名: YS-035 hydrochloride
• CAS号: 89805-39-0
• 分子量: 395.92
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₃₀ClNO₄
• 熔点: N/A
• 闪点: N/A

YS-035 hydrochloride用途

YS 035盐酸盐是一种钙离子的细胞摄取和线粒体外排的Ca2+拮抗剂。YS 035盐酸盐抑制肌肉细胞摄取Ca2+并抑制Na+/Ca2+交换(Ki=28µM)。YS 035盐酸盐是研究线粒体Ca2+转运的有用工具[1]。

YS-035 hydrochloride名称

• 英文名: 2-(3,4-Dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylethanaminium chloride

YS-035 hydrochloride生物活性

• 描述: YS 035盐酸盐是一种钙离子的细胞摄取和线粒体外排的Ca2+拮抗剂。YS 035盐酸盐抑制肌肉细胞摄取Ca2+并抑制Na+/Ca2+交换(Ki=28µM)。YS 035盐酸盐是研究线粒体Ca2+转运的有用工具[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钙通道
  研究领域 >> 神经疾病
• 参考文献:

  [1]. R Deana, et al. Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem J. 1984 Mar 15;218(3):899-905.

YS-035 hydrochloride物理化学性质

• 分子式: C₂₁H₃₀ClNO₄
• 分子量: 395.92
• 精确质量: 395.186340
• InChIKey: GYBONEHHSUABAO-UHFFFAOYSA-N
• SMILES: COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC.Cl
• 储存条件: -20°C，密闭，干燥

YS-035 hydrochloride靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1266185

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

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YS-035 hydrochloride英文别名

• Benzeneethanaminium, N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dimethoxy-N-methyl-, chloride (1:1)
• 2-(3,4-Dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylethanaminium chloride