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α类固醇脱氢酶

更新时间:2024-01-06 19:45:48

α类固醇脱氢酶结构式
α类固醇脱氢酶结构式
品牌特惠专场
常用名 α类固醇脱氢酶 英文名 3alpha-hydroxysteroid dehydrogenase
CAS号 9028-56-2 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A

 α类固醇脱氢酶用途


3α-羟基类固醇脱氢酶(3α-HSD)是一种由AKR1C4基因编码的酶,可以催化3-酮甾体转化为3α-羟化合物。3α-羟基类固醇脱氢酶在雄激素DHT的失活中起着重要作用,可将DHT转化为雄激素活性较弱的3α-雄甾二醇,可用于多毛症的研究[1]。

 α类固醇脱氢酶名称

中文名 类固醇脱氢酶
英文名 Dehydrogenase 3alpha-hydroxy steroid
中文别名 羟基甾族化合物氧化还原酶 | 羥固醇 | 3Α-羟基类固醇脱氢酶 | 类固醇脱氢酶 | 3Α羟基类固醇脱氢酶/羟基甾族化合物氧化还原酶/羟固醇/HSD
英文别名 更多

 α类固醇脱氢酶生物活性

描述 3α-羟基类固醇脱氢酶(3α-HSD)是一种由AKR1C4基因编码的酶,可以催化3-酮甾体转化为3α-羟化合物。3α-羟基类固醇脱氢酶在雄激素DHT的失活中起着重要作用,可将DHT转化为雄激素活性较弱的3α-雄甾二醇,可用于多毛症的研究[1]。
相关类别
参考文献

[1]. Anne Z Steiner, et al. 3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab. 2008 Apr;93(4):1298-303.   

 α类固醇脱氢酶物理化学性质

外观性状 ammonium sulfate suspension
储存条件 2-8°C

 α类固醇脱氢酶安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲) 24/25
危险品运输编码 NONH for all modes of transport
WGK德国 3

 α类固醇脱氢酶文献29

更多文献
Electronic effects of para-substitution on acetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase.

Bioorg. Med. Chem. 16 , 1084-9, (2008)

Stereoselective reductive metabolism of various p-substituted acetophenone derivatives was studied using isolated rat liver 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD). Kinetic experiments were p...

Enzyme biosensor for androsterone based on 3α-hydroxysteroid dehydrogenase immobilized onto a carbon nanotubes/ionic liquid/NAD+ composite electrode.

Talanta 99 , 697-702, (2012)

A 3α-hydrosteroid biosensor for androsterone determination has been prepared by immobilizing the enzyme 3α-hydroxysteroid dehydrogenase (3α-HSD) in a composite electrode platform constituted of a mixt...

Prostaglandin dehydrogenase activity of purified rat liver 3 alpha-hydroxysteroid dehydrogenase.

Biochem. Biophys. Res. Commun. 148(2) , 646-52, (1987)

Homogeneous 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) from rat liver cytosol displays 9, 11, and 15-hydroxyprostaglandin dehydrogenase activity. Using [14C]-PGF2 alpha as substrate the produc...

 α类固醇脱氢酶英文别名

ALPHA-HYDROXYSTEROID DEHYDROGENASE
3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE
EC 1.1.1.50
EC: 1.1.1.50
3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg
3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni
Dehydrogenase, 3alpha-hydroxy steroid
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