奥美拉唑镁

• 常用名: 奥美拉唑镁
• 英文名: Omeprazole magnesium
• CAS号: 95382-33-5
• 分子量: 713.121
• 密度: N/A
• 沸点: 600ºC at 760mmHg
• 分子式: C₁₇H₁₉MgN₃O₃S
• 熔点: N/A
• 闪点: 316.7ºC

奥美拉唑镁用途

奥美拉唑镁是一种口服活性质子泵抑制剂(PPI),可以抑制胃酸。奥美拉唑镁可用于酸反流相关症状和频繁烧心的研究[1][2]。

奥美拉唑镁名称

• 中文名: 奥美拉唑镁
• 英文名: Magnesium,bis[6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, (T-4)

奥美拉唑镁生物活性

• 描述: 奥美拉唑镁是一种口服活性质子泵抑制剂(PPI),可以抑制胃酸。奥美拉唑镁可用于酸反流相关症状和频繁烧心的研究[1][2]。
• 相关类别:
  研究领域 >> 代谢疾病
  信号通路 >> 跨膜转运 >> 质子泵
• 参考文献:

  [1]. Holt S, et al. Omeprazole. Overview and opinion. Dig Dis Sci. 1991 Apr;36(4):385-93.

  [2]. Allgood LD, et al. Comparison of Prilosec OTC (omeprazole magnesium 20.6 mg) to placebo for 14 days in the treatment of frequent heartburn. J Clin Pharm Ther. 2005 Apr;30(2):105-12.

奥美拉唑镁物理化学性质

• 沸点: 600ºC at 760mmHg
• 分子式: C₁₇H₁₉MgN₃O₃S
• 分子量: 713.121
• 闪点: 316.7ºC
• 精确质量: 712.198792
• PSA: 96.31000
• LogP: 3.76540
• InChIKey: MQEUGMWHWPYFDD-UHFFFAOYSA-N
• SMILES: COc1ccc2nc(S(=O)Cc3ncc(C)c(OC)c3C)[nH]c2c1.[Mg]
• 水溶解性: Very slightly soluble in water, sparingly soluble in methanol, practically insoluble in heptane.

奥美拉唑镁安全信息

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933990090

奥美拉唑镁海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

奥美拉唑镁靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4296185

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

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奥美拉唑镁英文别名

• Esmolol Hydrochloride (100 mg)
• MONOCLONAL ANTI-EDG-4 (ENDOTHELIAL CELL
• EsmololHclC16H25No4Hcl
• methyl 3-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]propionate Hydrochloride
• 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoicacidmethylest
• ESMOLOL HCL
• Gastracid
• Omep
• Ome-Puren
• Gastroloc
• (S)-omeprazole magnesium
• bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]suIfinyl]-1H-benzimidazole-1-yl)
• Antra
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (2:1)
• Brevibloc
• EsMolol Hcl API
• Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate hydrochloride
• Magnesium bis(5-methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide)
• Omebeta
• Omeprazole magnesium