12-羟基-8(17),13-赖百当二烯-16,15-内酯

• 常用名: 12-羟基-8(17),13-赖百当二烯-16,15-内酯
• 英文名: Epivitexolide D
• CAS号: 958885-86-4
• 分子量: 318.45
• 密度: 1.1±0.1 g/cm3
• 沸点: 468.0±20.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₃
• 熔点: N/A
• 闪点: 187.5±14.5 °C

12-羟基-8(17),13-赖百当二烯-16,15-内酯用途

牡荆内酯E是一种二萜化合物,从马来西亚牡荆属植物的叶子中分离得到。维生素E对HCT-116癌细胞系和人胎肺成纤维细胞MRC5细胞系显示出细胞毒性作用【1】。

12-羟基-8(17),13-赖百当二烯-16,15-内酯名称

• 中文名: 12-羟基-8(17),13-赖百当二烯-16,15-内酯
• 英文名: 12-Hydroxy-8(17),13-labdadien-16,15-olide

12-羟基-8(17),13-赖百当二烯-16,15-内酯生物活性

• 描述: 牡荆内酯E是一种二萜化合物,从马来西亚牡荆属植物的叶子中分离得到。维生素E对HCT-116癌细胞系和人胎肺成纤维细胞MRC5细胞系显示出细胞毒性作用【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Corlay N, et al. Antibacterial Labdane Diterpenoids from Vitex vestita. J Nat Prod. 2015;78(6):1348-1356.

12-羟基-8(17),13-赖百当二烯-16,15-内酯物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 468.0±20.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₃
• 分子量: 318.45
• 闪点: 187.5±14.5 °C
• 精确质量: 318.219482
• PSA: 46.53000
• LogP: 5.46
• InChIKey: NNNUJNWMFLYQTF-PFRQMTDMSA-N
• SMILES: C=C1CCC2C(C)(C)CCCC2(C)C1CC(O)C1=CCOC1=O
• 外观性状: 粉末
• 蒸汽压: 0.0±2.6 mmHg at 25°C
• 折射率: 1.535
• 储存条件: 2-8℃，干燥，密闭

12-羟基-8(17),13-赖百当二烯-16,15-内酯安全信息

• 危害码 (欧洲): Xi

12-羟基-8(17),13-赖百当二烯-16,15-内酯靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 0.1 uM incuba... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394976

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实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 5 uM incubate... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394979

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 20 uM incubat... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394980

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394981

实验名称：Cytotoxicity against human K562 cells assessed as cell viability at 30 uM 来源：ChEMBL 靶标：K562 External Id：CHEMBL1107377

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394982

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394983

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394974

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394975

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12-羟基-8(17),13-赖百当二烯-16,15-内酯英文别名

• 3-{(1R)-1-Hydroxy-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethyl}-2(5H)-furanone