安吡昔康

• 常用名: 安吡昔康
• 英文名: ampiroxicam
• CAS号: 99464-64-9
• 分子量: 447.462
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₀H₂₁N₃O₇S
• 熔点: 159-161?C
• 闪点: N/A
• 符号: GHS07
• 信号词: Warning

安吡昔康用途

Ampiroxicam(CP65703)是非选择性的环氧化酶抑制剂,有抗炎活性。

安吡昔康名称

• 中文名: 安吡昔康
• 英文名: ampiroxicam
• 中文别名: 索非那新琥珀酸盐 | 4-[1-(乙氧羰基氧)-乙氧基]-2-甲基-N-(2-吡啶基)-2H-苯并噻嗪-3-甲酰胺-1,1-二氧化物 | 安碧罗康

安吡昔康生物活性

• 描述: Ampiroxicam(CP65703)是非选择性的环氧化酶抑制剂,有抗炎活性。
• 相关类别:
  天然产物 >> 生物碱
  研究领域 >> 炎症/免疫
• 靶点实验:

  COX

• 参考文献:

  [1]. Aoki T, et al. Premedication with cyclooxygenase-2 inhibitor meloxicam reduced postoperative pain in patients after oral surgery. Int J Oral Maxillofac Surg. 2006 Jul;35(7):613-7.

  [2]. Sasaki, T., et al., Antigenic characterization in ampiroxicam-induced photosensitivity using an in vivo model of contact hypersensitivity. J Dermatol Sci, 1999. 21(3): p. 170-5.

安吡昔康物理化学性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 159-161?C
• 分子式: C₂₀H₂₁N₃O₇S
• 分子量: 447.462
• 精确质量: 447.110016
• PSA: 132.51000
• LogP: 3.12
• InChIKey: LSNWBKACGXCGAJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)OC(C)OC1=C(C(=O)Nc2ccccn2)N(C)S(=O)(=O)c2ccccc21
• 折射率: 1.630
• 储存条件: -20°C Freezer

安吡昔康安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 警示性声明: P301 + P312 + P330
• 危险品运输编码: NONH for all modes of transport
• RTECS号: FG1602400
• 海关编码: 2942000000

安吡昔康海关

• 海关编码: 2942000000

安吡昔康靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green ... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_green

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio ... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_ratio

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue c... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_blue

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EM141217_green

实验名称：insulin secretion from INS-1E cells in the presence of 5 mM glucose-screen 来源：846 靶标：N/A External Id：5mMGluc_INS1E_InsulinRelease_40mMGluc_SP

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安吡昔康英文别名

• (±)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester) 1,1-dioxide
• Ethyl 1-{[2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate
• ampiroxicam
• 4-{1-[(Ethoxycarbonyl)oxy]ethoxy}-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide S,S-dioxide
• Ethyl 1-{[2-methyl-1,1-dioxido-3-(2-pyridinylcarbamoyl)-2H-1,2-benzothiazin-4-yl]oxy}ethyl carbonate
• 4-[1-(Ethoxycarbonyloxy)ethoxy]-2-methyl-N-(pyridin-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide
• Ampiroxicamum [Latin]
• MFCD00866079
• 4-[1-(Ethoxycarbonyloxy)ethoxy]-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide
• Flucam
• Carbonic acid, ethyl 1-[[2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester
• ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1λ⁶,2-benzothiazin-4-yl]oxy]ethyl carbonate
• Ampiroxicamum