Direct synthesis of ester-containing indium homoenolate and its application in palladium-catalyzed cross-coupling with aryl halide

…, CHA Wong, YS Yang, YC Lai, HL Cheong…

Index: Shen, Zhi-Liang; Goh, Kelvin Kau Kiat; Wong, Colin Hong An; Yang, Yong-Sheng; Lai, Yin-Chang; Cheong, Hao-Lun; Loh, Teck-Peng Chemical Communications, 2011 , vol. 47, # 16 p. 4778 - 4780

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Citation Number: 13

Abstract

An efficient method for the synthesis of ester-containing indium homoenolatevia a direct insertion of indium into β-halo ester in the presence of CuI/LiCl was described. The synthetic utility of the indium homoenolate was demonstrated by palladium-catalyzed cross-coupling with aryl halides in DMA with wide functional group compatibility.