Tetrahedron Letters

A chemoselective deoxygenation of N-oxides by sodium borohydride–Raney nickel in water

NB Gowda, GK Rao, RA Ramakrishna

Index: Gowda, Narendra B.; Rao, Gopal Krishna; Ramakrishna, Ramesha A. Tetrahedron Letters, 2010 , vol. 51, # 43 p. 5690 - 5693

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Citation Number: 6

Abstract

A simple and convenient protocol for deoxygenation of aliphatic and aromatic N-oxides to the corresponding amines in good to excellent yield using sodium borohydride–Raney nickel in water is reported. Other functional moieties such as alkenes, halides, ethers, and amides are unaffected under the present reaction condition.