RSC Advances

Solvent-free aryl amination catalysed by [Pd (NHC)] complexes

A Chartoire, A Boreux, AR Martin, SP Nolan

Index: Chartoire, Anthony; Boreux, Arnaud; Martin, Anthony R.; Nolan, Steven P. RSC Advances, 2013 , vol. 3, # 12 p. 3840 - 3843

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Citation Number: 21

Abstract

A highly effective solvent-free protocol for the Buchwald–Hartwig amination of unactivated aryl chlorides is described. The effect of various [Pd (NHC)] pre-catalyst systems on the reactivity has been studied.[Pd (IPr*)(cin) Cl] is reported as the complex of choice for the transformation.

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