Tetrahedron letters

An improved method for the palladium-catalyzed amination of aryl triflates

J Åhman, SL Buchwald

Index: Ahman, Jens; Buchwald, Stephen L. Tetrahedron Letters, 1997 , vol. 38, # 36 p. 6363 - 6366

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Citation Number: 109

Abstract

Aryl triflates are coupled with amines using catalytic amounts of Pd (OAc) 2 and BINAP and Cs2CO3 as a stoichiometric base. This protocol allows for the efficient amination of electron- poor as well as electron-rich aryl triflates and the reaction conditions are compatible with a wide variety of functional groups.© 1997 Elsevier Science Ltd.