A Novel Domino Synthesis of Quinazolinediones by Palladium??Catalyzed Double Carbonylation

…, H Neumann, M Beller, XF Wu

Index: Li, Haoquan; Neumann, Helfried; Beller, Matthias; Wu, Xiao-Feng Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3183 - 3186 Angew. Chem., 2014 , vol. 126, # 12 p. 3247 - 3250,4

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Citation Number: 15

Abstract

Abstract Combining commercially available bromoanilines and bromobenzonitriles in a novel double carbonylation process allows for a straightforward synthesis of isoindolo [1, 2- b] quinazoline-10, 12-diones. At least five different C [BOND] C and/or C [BOND] N bonds

~80%

~63%

~49%

~83%

~81%

~88%

~88%

~81%

~82%

~82%

~62%

~71%

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Detail

~80%

~88%

~81%

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~77%

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Detail

~88%

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