Phenyl benzoate

Modify Date: 2024-01-02 17:03:06

Phenyl benzoate Structure
Phenyl benzoate structure
Common Name Phenyl benzoate
CAS Number 93-99-2 Molecular Weight 198.217
Density 1.1±0.1 g/cm3 Boiling Point 314.0±11.0 °C at 760 mmHg
Molecular Formula C13H10O2 Melting Point 68-70 °C(lit.)
MSDS Chinese USA Flash Point 128.9±16.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Phenyl benzoate


Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid. Phenyl benzoate is a chloride transport blocker, inhibits Cl--dependent Glu accumulation into vesicles. Phenyl benzoate can be used as preservative in cosmetic products[1][2].

 Names

Name phenyl benzoate
Synonym More Synonyms

 Phenyl benzoate Biological Activity

Description Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid. Phenyl benzoate is a chloride transport blocker, inhibits Cl--dependent Glu accumulation into vesicles. Phenyl benzoate can be used as preservative in cosmetic products[1][2].
Related Catalog
In Vitro Phenyl benzoate (DPC) (0.1 μM-1 mM; 15 min) inhibits the Ca2+/Cl--dependent and -independent L-[3H]Glu (100 nM) binding to rat brain membranes[1].

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 314.0±11.0 °C at 760 mmHg
Melting Point 68-70 °C(lit.)
Molecular Formula C13H10O2
Molecular Weight 198.217
Flash Point 128.9±16.7 °C
Exact Mass 198.068085
PSA 26.30000
LogP 3.59
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.585
Stability Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH6299500
CHEMICAL NAME :
Benzoic acid, phenyl ester
CAS REGISTRY NUMBER :
93-99-2
BEILSTEIN REFERENCE NO. :
1566346
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H10-O2
MOLECULAR WEIGHT :
198.23
WISWESSER LINE NOTATION :
RVOR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,1179,1969

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DH6299500
HS Code 2916310090

 Synthetic Route

 Customs

HS Code 2916310090
Summary 2916310090 other benzoic acid and its salts and esters。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Articles9

More Articles
Pressurized liquid extraction-gas chromatography-mass spectrometry for confirming the photo-induced generation of dioxin-like derivatives and other cosmetic preservative photoproducts on artificial skin.

J. Chromatogr. A. 1440 , 37-44, (2016)

The stability and photochemical transformations of cosmetic preservatives in topical applications exposed to UV-light is a serious but poorly understood problem. In this study, a high throughput extra...

Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes.

J. Appl. Toxicol. 36 , 1129-36, (2016)

In vitro testing methods for classifying sensitizers could be valuable alternatives to in vivo sensitization testing using animal models, such as the murine local lymph node assay (LLNA) and the guine...

Chloride current activated by cyclic AMP and parathyroid hormone in rat osteoblasts.

Pflugers Arch. 415(1) , 104-14, (1989)

In primary cultures of rat osteoblasts, studied with the whole-cell configuration of the patch-clamp technique, 8-bromo-cyclic AMP (8BrcAMP) forskolin (FS) and 1-34 parathyroid hormone (PTH) were show...

 Synonyms

Diphenylcarboxylate
Phenyl benzoate
Phenol,benzoate
MFCD00003072
Phenol, benzoate (7CI)
EINECS 202-293-2
benzenecarboxylic acid phenyl ester
Benzoic acid phenyl ester
Benzoic acid,phenyl ester
UNII-B8A3WVZ590
Benzoic acid, phenyl ester
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