Synthesis and pharmacological activity of 4-aryl-l, 4-dihydropyridines

VV Kastron, GY Dubur, RO Vitolin', AA Kimenis…

Index: Kastron, V. V.; Dubur, G. Ya.; Vitolin', R. O.; Kimenis, A. A.; Selga, M. Ya.; et al. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 11 p. 817 - 824 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 11 p. 1322 - 1329

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Abstract

The antiphage activity of the compounds was determined in a phage-bacterium system (DNA-containing phage T6 and E. coli, and RNA-containing phage Ms-2 and E. coli HFrl). The number of surviving phage particles was determined by Grazia's agar slope method. Antiphage activity was expressed as percentage inactivation, calculated by the formula [3]:[i- (No/Nk)]" 100%, where No is the number of surviving phage particles in the test, and N k ...