Condensation of aromatic aldehydes with N, N-dimethylacetamide in presence of dialkyl carbonates as dehydrating agents

T Weidlich, L Prokeš, A Růžička…

Index: Weidlich, Tomas; Prokes, Lubomir; Ruzicka, Ales; Padelkova, Zdenka Monatshefte fur Chemie, 2010 , vol. 141, # 2 p. 205 - 211

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Citation Number: 4

Abstract

Abstract Reactions of benzaldehydes with excess N, N-dimethylacetamide at 140° C in the presence of diethyl carbonate as dehydrating agent and a base gave (E)-N, N- dimethylcinnamamides in good yields. If hydroxybenzaldehydes are used as substrates the reaction is accompanied by alkylation. Graphical abstract