Efficient palladium (II) catalysis under air. Base-free oxidative heck reactions at room temperature or with microwave heating

J Lindh, PA Enquist, Å Pilotti, P Nilsson…

Index: Lindh, Jonas; Enquist, Per-Anders; Pilotti, Ake; Nilsson, Peter; Larhed, Mats Journal of Organic Chemistry, 2007 , vol. 72, # 21 p. 7957 - 7962

Full Text: HTML

Citation Number: 108

Abstract

Scope and limitations of the base-free oxidative Heck reaction with arylboronic acids have been explored. Under our conditions, the dmphen-palladium (II)-catalyzed arylation proceeded with air or p-benzoquinone as reoxidants of palladium (0). We found that ambient temperature and mild aerobic conditions allow for the use of substrates sensitive to palladium (II)-catalyzed oxidation. Oxidative Heck couplings, employing different ...